Results 91 to 100 of about 117,949 (253)

Double administration of self-complementary AAV9NDUFS4 prevents Leigh disease in Ndufs4-/- mice. [PDF]

Brain, 2022
Corrà S, Cerutti R, Balmaceda V, Viscomi C, Zeviani M.   +4 more
europepmc   +1 more source

‘I, Me, Myself’: Selfhood and Melancholy in the Journals of Gertrude Savile (1697–1758)

Journal for Eighteenth-Century Studies, EarlyView.
Abstract This article examines the journals of Gertrude Savile from 1727 in light of recent scholarship on early modern and eighteenth‐century melancholy. The concept had myriad associations with medicine, physiology, the imagination, and feeling, but questions remain about how melancholy during this period was considered by those outside the narrow ...
Daniel Beaumont
wiley   +1 more source

Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale. [PDF]

, 2017
BACKGROUND: Acute decompensated heart failure (ADHF) is a leading cause of hospitalization in older persons in the United States. Reduced physical function and frailty are major determinants of adverse outcomes in older patients with hospitalized ADHF ...
Duncan, Pamela, Eggebeen, Joel D., Hewston, Leigh Ann, Kitzman, Dalane W., Mentz, Robert J., Morgan, Timothy M., O\u27Connor, Christopher M., Pastva, Amy M., Reed, Shelby D., Reeves, Gordon R., Rejeski, W. Jack, Rosenberg, Paul B., Whellan, David J.   +12 more
core   +2 more sources

Is Prescribing Interval Doses of Low Dose Oral Corticosteroids Still Considered Safe Treatment for Chronic Rhinosinusitis With Nasal Polyposis?

The Laryngoscope, EarlyView.
Maryam Khalifa, Brian W. Rotenberg, Leigh J Sowerby   +2 more
wiley   +1 more source

Genotyping Contemporary Captive and Historical Wild Western Lowland Gorillas Indicates Captive Breeding Is Maintaining Genetic Diversity in a Critically Endangered Primate

Animal Conservation, EarlyView.
Captive populations of threatened species risk losing genetic diversity over time. We evaluated the genetic status of contemporary captive western lowland gorillas (Gorilla gorilla gorilla) at Howletts and Port Lympne and compared this with specimens from a historical wild population.
Jaimie Morris, Tony King, John Hills, Simon C. Harvey, Jane Hopper, Rodrigo Vega   +5 more
wiley   +1 more source

Congenital myasthenic syndrome in Golden Retrievers is associated with a novel COLQ mutation. [PDF]

, 2020
BackgroundCongenital myasthenic syndromes (CMSs) are a group of inherited disorders of neuromuscular transmission that may be presynaptic, synaptic, or postsynaptic.
Anderson, Kendall J, Clark, Leigh Anne, Evans, Jacquelyn M, Guo, Ling T, Knipe, Marguerite, Shelton, G Diane, Sturges, Beverly K, Tsai, Kate L, Vernau, Karen M, Williams, D Colette, Winger, Kathryn, Zwueste, Danielle M   +11 more
core  

Environmental Stress Drives Plasticity in Sexual Bimaturism in the Black Soldier Fly (Hermetia illucens Linnaeus, 1758)

Entomologia Experimentalis et Applicata, EarlyView.
We measured the plasticity in sexual bimaturism (SBM; differences between sexes in the timing of sexual maturity) in the black soldier fly (BSF) by exposing larvae to nutrient availability and humidity stress. Our results show that SBM can range between protandry and protogyny depending on the environmental quality. Additionally, we found the degree of
Luis Rodrigo Arce‐Valdés, Hayat Mahdjoub, Jordi Vilanova, Carlos López‐Manzano, Rassim Khelifa   +4 more
wiley   +1 more source

A Comprehensive Approach to the Diagnosis of Leigh Syndrome Spectrum

Diagnostics
Background: Leigh syndrome spectrum (LSS) is a novel nomenclature that encompasses both classical Leigh syndrome and Leigh-like phenotypes. Given the heterogeneity of disease presentation, a new consensus published recently addressed the main issues and ...
Manuela Schubert Baldo, Luísa Azevedo, Margarida Paiva Coelho, Esmeralda Martins, Laura Vilarinho   +4 more
doaj   +1 more source

Leigh Syndrome: Report of a Rare Case with Late Onset Presentation

مجله كليه طب الكندي, 2018
Leigh's syndrome, or sub acute necrotizing encephalomyelopathy, is a rare inherited neurometabolic disease of infancy and early childhood with variable course and prognosis. Rarely, it occurs in juveniles and adults. The diagnosis is difficult and still
Qays A. Hassan
doaj   +1 more source

Felons’ chattels and English living standards in the later fourteenth and fifteenth centuries

The Economic History Review, EarlyView.
Abstract The later fourteenth and fifteenth centuries have long occupied an intriguing and contested place in discussions of England's long‐run economic development. One key issue around which debate has coalesced is the living standards of the population as a whole and of different groups within it. We contribute to this debate by bringing forward new
Chris Briggs, Ben Jervis, Alice Forward, Tomasz Gromelski, Matthew Tompkins   +4 more
wiley   +1 more source