Anesthetic Management of Leigh Syndrome
Bezmiâlem Science, 2017 Leigh syndrome is an extremely rare disorder in infants and children. It is characterized by a progressive neurodegenerative course with subacute necrotizing encephalomyelopathy, and it presents with developmental delay, seizures, dysarthria, ataxia, and
Ayşe Çiğdem TÜTÜNCÜ +2 more
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Review for "Genotype‐phenotype analysis of MT‐ATP6 ‐associated Leigh syndrome"
, 2021 Yi Shiau Ng
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Coenzyme Q10 deficiencies: pathways in yeast and humans. [PDF]
, 2018 Coenzyme Q (ubiquinone or CoQ) is an essential lipid that plays a role in mitochondrial respiratory electron transport and serves as an important antioxidant.
Awad, Agape M +5 more
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Connective tissue involvement in an m.10191 T > C carrier with Leigh-like syndrome [PDF]
, 2023 Josef Finsterer, Shaundra M. Newstead
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Leigh Syndrome: Report of a Rare Case with Late Onset Presentation
مجله كليه طب الكندي, 2018 Leigh's syndrome, or sub acute necrotizing encephalomyelopathy, is a rare inherited neurometabolic disease of infancy and early childhood with variable course and prognosis. Rarely, it occurs in juveniles and adults. The diagnosis is difficult and still
Qays A. Hassan
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Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization and Cell Survival in Various Mitochondrial Diseases [PDF]
, 2017 Mitochondrial dysfunction increases oxidative stress and depletes ATP in a variety of disorders. Several antioxidant therapies and drugs affecting mitochondrial biogenesis are undergoing investigation, although not all of them have demonstrated favorable
Abe Takaaki +41 more
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Targeting the expressive language of children with Down syndrome who are minimally verbal : bridging research and practice [PDF]
, 2014 textChildren with Down syndrome present with an array of physical and cognitive sequelae that can hinder speech and language development. These individuals can constitute a considerable portion of a speech-language pathologist’s caseload.
Kara, Rachael Leigh 1981-
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Power, competition, and the nature of history [PDF]
, 2019 Historians have debated whether pathways and events from the past to the present are influenced largely by contingency, the dependence of outcomes on particular prior conditions, or whether there is long-term emergent directional change.
Vermeij, Geerat J
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IFNγ modestly contributes to disease progression in the Ndufs4 (-/-) model of Leigh syndrome while IP10 is dispensable [PDF]
, 2023 Allison R. Hanaford +13 more
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