Results 21 to 30 of about 50,358 (293)

PLAG1-Rearrangment in a Uterine Leiomyosarcoma with Myxoid Stroma and Heterologous Differentiation

Genes, Chromosomes and Cancer, 2021
A variety of molecular alterations have been reported in uterine leiomyosarcomas, but most are considered nondiagnostic. There are, however, rare exceptions including PLAG1 rearrangement which has recently been identified in a subset of myxoid ...
S. Thiryayi, G. Turashvili, E. Latta, D. Swanson, Lei Zhang, C. Antonescu, B. Dickson   +6 more
semanticscholar   +1 more source

Primary urachal leiomyosarcoma: A rare case report and literature review

Urology Case Reports, 2022
Primary urachal leiomyosarcoma is rare entity with unclear prognosis and treatment strategy. We report a case of urachal leiomyosarcoma presenting, and treated with open urachal tumor resection and partial cystectomy.
Shijie Tong, Zhankui Jia
doaj   +1 more source

Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients—A Position Paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN)

Cancers, 2021
Simple Summary In this position paper, we aim to summarize state-of-the-art treatments for patients with leiomyosarcomas in order to identify knowledge gaps and current unmet needs, thereby guiding the community to design innovative clinical trials and ...
B. Kasper, Annie Achee, K. Schuster, R. Wilson, G. van Oortmerssen, R. Gladdy, Matthew L. Hemming, Paul H. Huang, M. Ingham, Robin L. Jones, S. Pollack, D. Reinke, R. Sanfilippo, S. Schuetze, N. Somaiah, B. V. Van Tine, B. Wilky, S. Okuno, J. Trent   +18 more
semanticscholar   +1 more source

“Pushing the margin:” utilization of renal autotransplantation to achieve complete resection in vena caval leiomyosarcomas

Journal of Pediatric Surgery Case Reports, 2020
We report the case of a 19-year-old female who underwent resection of the sub- and infrahepatic inferior vena cava (IVC) with concomitant left kidney autotransplantation for leiomyosarcoma.
Joseph Anderson, Vinayak Rohan, Helen Grey, Satish N. Nadig   +3 more
doaj   +1 more source

Genomic Database Analysis of Uterine Leiomyosarcoma Mutational Profile

Cancers, 2020
Uterine Leiomyosarcoma (uLMS) is by far the most common type of uterine sarcoma, characterized by an aggressive clinical course, a heterogeneous genetic profile and a very scarce response to cytotoxic chemotherapy.
A. Astolfi, M. Nannini, V. Indio, Angela Schipani, A. Rizzo, A. Perrone, P. De Iaco, M. Pirini, A. De Leo, M. Urbini, P. Secchiero, M. Pantaleo   +11 more
semanticscholar   +1 more source

Metastases of soft tissue sarcoma to the liver: A Historical Cohort Study from a Hospital‐based Cancer Registry [PDF]

, 2020
Background: Hepatic metastasis of soft tissue sarcoma is rare compared to lung metastasis, and the literature is scarce. We examined the risk of hepatic metastasis according to the site of occurrence and histological type.
Harabayashi, Toru, Sagawa, Tamotsu, Hiroaki Hiraga, Toru Harabayashi, Wataru Sakai, Matsuoka, Masatake, Toshikazu Nambu, Toshiki Shinohara, Hiroyuki Kato, Tamotsu Sagawa, Adachi, Hirohumi, Suzuki, Hiroaki, Nishiyama, Noriaki, Ryuta Arai, Hidenori Kato, Tamotsu Soma, Kato, Hidenori, Masatake Matsuoka, Soma, Tamotsu, Nambu, Toshikazu, Kato, Hiroyuki, Okamoto, Masanori, Shinohara, Toshiki, Noriaki Nishiyama, Arai, Ryuta, Sakai, Wataru, Hirohumi Adachi, Hiroaki Suzuki, Masanori Okamoto, Hiraga, Hiroaki   +29 more
core   +1 more source

Primary intratesticular pleomorphic leiomyosarcoma: A rare case report

Indian Journal of Pathology and Microbiology, 2013
Intratesticular leiomyosarcoma is an extremely rare tumor of the genitourinary system. We report a case of intratesticular pleomorphic leiomyosarcoma in a 68-year-old male who presented with gradual painless enlargement of the right scrotal mass over a ...
Rajshri Pisaram Damle, Kishor H Suryawanshi, Nandkumar V Dravid, Dhananjay V Newadkar   +3 more
doaj   +1 more source

Stathmin expression alters the antiproliferative effect of eribulin in leiomyosarcoma cells

Journal of Pharmacological Sciences, 2022
Uterine leiomyosarcoma is an aggressive soft tissue tumor. Stathmin, a phosphoprotein that modulates microtubule dynamics, is highly expressed in many malignancies including leiomyosarcoma.
Mana Azumi, Mikihiro Yoshie, Nami Nakachi, Atsuya Tsuru, Kazuya Kusama, Kazuhiro Tamura   +5 more
doaj   +1 more source

Cutaneous leiomyosarcoma: dermal and subcutaneous [PDF]

, 2020
BACKGROUND AND OBJECTIVES: Leiomyosarcoma of skin (LMS) can be sub-classified on pathology appearances as Dermal or Subcutaneous. The aim of this study was to provide treatment recommendations for these uncommon tumours.
Wong, GN, Slavin, J, Gyorki, D, Webb, A, Ngan, SY, Henderson, MA, Tran, P, McCormack, C   +7 more
core   +1 more source

Leiomyosarcoma With Alternative Lengthening of Telomeres Is Associated With Aggressive Histologic Features, Loss of ATRX Expression, and Poor Clinical Outcome [PDF]

, 2017
Leiomyosarcoma is an aggressive soft tissue sarcoma with poor patient survival. Recently, it was shown that 53% to 62% of leiomyosarcomas use the alternative lengthening of telomeres (ALT) as their telomere maintenance mechanism.
Liau, Jau-Yu;Tsai, Jia-Huei;Jeng, Yung-Ming;Lee, Jen-Chieh;Hsu, Hung-Han;Yang, Ching-Yao, 鄭永銘;李仁傑;蔡佳惠;楊卿堯;廖肇裕   +1 more
core   +1 more source