Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Primary hepatic leiomyosarcoma in a 5-month-old female infant
Leiomyosarcoma is a malignant mesenchymal neoplasm deriving from the smooth muscle cells. Primary hepatic leiomyosarcoma is very rare. Its onset is always during middle and old age. Herein, we present a case of primary hepatic leiomyosarcoma in a 5-month-
Pei-Shan Tsai +2 more
doaj +1 more source
Giant Leiomyosarcoma of the Urinary Bladder [PDF]
The bladder leiomyosarcoma is a rare and agressive mesenchymal tumour, and adult women of reproductive age have a higher incidence of developing the bladder leiomyosarcoma.
José G.A. Ribeiro +4 more
doaj +1 more source
Small Bowel Cancer: Implications of Preoperative Work‐Up on Surgical Strategy
Small bowel cancers comprise a heterogeneous group of malignancies, making diagnosis and treatment challenging. This study aimed to evaluate the ability of preoperative diagnostic work‐up to predict clinical and histopathological findings, facilitate subgroup identification, and support tailored, individualized surgical strategies. Preoperative work‐up
Erik Kjæstad +4 more
wiley +1 more source
A rare case of primary renal leiomyosarcoma with peritoneal sarcomatosis – A case report
Primary renal leiomyosarcoma is an extremely rare renal malignancy. This case report presents clinicopathological and immunophenotypic features of a case of primary renal leiomyosarcoma with peritoneal sarcomatosis.
Maruthi D. Karri +4 more
doaj +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source
Current approaches in nanostructured biomaterials in treatment of leiomyosarcoma
One form of uncommon cancer that develops in the smooth muscles is called leiomyosarcoma, or LMS. The body's hollow organs, such as the stomach, bladder, intestines, and blood vessels, contain smooth muscles.
Shraddha Vikas Jadhav +4 more
doaj +1 more source
Interventional oncology in children: Where are we now?
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel +1 more
wiley +1 more source
What anabolic–androgenic steroids reveal about the limits of current harm reduction models
Abstract Background Harm reduction has largely been shaped by responses to psychoactive drug use where the most urgent harms are acute. These models focus on overdose, blood‐borne viruses, and rapid‐onset toxicity related harms. When applied wholesale to anabolic–androgenic steroids (AAS), they obscure the distinctive pharmacology, consumer typologies,
Timothy Piatkowski +2 more
wiley +1 more source
Mesenteric Lymph Node Recurrence of a Primary Colorectal Leiomyosarcoma
Primary colorectal leiomyosarcoma is an excessively rare entity. It is associated with an aggressive behavior and typically favor hematogenous spread. The current standard of care is surgical resection.
Amélie Beauchamp +5 more
doaj +1 more source

