Results 231 to 240 of about 35,146 (250)
Some of the next articles are maybe not open access.
Chromosome size polymorphisms of Leishmania donovani
Molecular and Biochemical Parasitology, 1987A minimum of 22 chromosomes were found in all Leishmania donovani stocks examined by orthogonal field alternation gel electrophoresis (OFAGE). Chromosome sizes ranged from approximately 270 to 4000 kb. Certain chromosomes were polymorphic in size between stocks and chromosomes present in some stocks had no apparent equivalent in others.
R P, Bishop, M A, Miles
openaire +2 more sources
Leishmania donovani (Ross 1903)
1995Visceral leishmaniasis, also known as kala-azar, has a wide distribution; no accurate estimate of its prevalence is currently available. The protozoan species that causes visceral leishmaniasis varies according to geographic regions; each has its own unique sandfly vectors and resevoir hosts.1 In India, Bangladesh, Nepal, and China the infection is ...
Dickson D. Despommier +2 more
openaire +1 more source
In Vitro Tryptophan Catabolism by Leishmania donovani donovani Promastigotes
The Journal of Protozoology, 1992ABSTRACT. Metabolism of tryptophan by promastigotes of Leishmania donovani donovani was investigated in cells suspended in a simple buffer solution supplemented with glucose. Metabolites from supernatant and lysed cell pellets were analyzed by capillary gas liquid chromatography and 13C nuclear magnetic resonance spectroscopy, with structural ...
S, Leelayoova +4 more
openaire +2 more sources
Characterization of strains of Leishmania donovani
Experimental Parasitology, 1966Abstract Even with the most standardized procedures yet available for in vivo trials, the intrastrain variations in the course of infection of Leishmania donovani in the hamster permit no easy assessment of variations among those tested by us from several parts of the world.
openaire +2 more sources
Oxidation of Leucine by Leishmania donovani
The Journal of Protozoology, 1991ABSTRACT. The metabolism of leucine by Leishmania donovani was investigated. Washed promastigotes were incubated with (1‐14C]‐or [U‐14C]leucine or [1 ‐14C]α‐ketoisocaproate (KIC) and 14C02 release was measured. The amount of KIC‐derived acetyl‐CoA oxidized in the citric acid cycle was computed. Promastigotes from mid‐stationary phase cultures oxidized
openaire +2 more sources
Leishmania donovani Tryparedoxin Peroxidase
2004Leishmanien sind intrazelluläre Parasiten, die für die Krankheit Leishmaniasis verantwortlich sind. Die Suche nach Therapieansätzen ergab, dass der Trypanothione-vermittelte Hydroperoxide-Metabolismus die "Achilles-Sehne" dieser Trypanosomatiden ist, da sie dem Angriff von ROS (Reactive Oxyzen Species) ausgesetzt sind, die dem aeroben Stoffwechsel des ...
openaire +1 more source
Macromolecular Synthesis in Leishmania donovani Amastigotes
The Journal of Parasitology, 1985Amastigotes (non-flagellated tissue forms) of Leishmania sp. reside and multiply within the phagolysosomes in tissue macrophages of vertebrate hosts. They are true obligate, intracellular parasites and do not persist as viable entities outside of host cells.
openaire +2 more sources
Cellular Immunity to Leishmania Donovani
The Journal of Immunology, 1974Abstract C57BL/6J mice were subjected to various combinations of immunosuppressive treatments and infected i.v. with amastigotes of Leishmania donovani. In normal mice the parasite population reached its peak about 24 days post-infection, after which parasite numbers gradually declined but they were still detectable on day 60. The course
Clare B Skov, Donald W Twohy
openaire +1 more source
Leishmania donovani parasitaemia in Kenyan visceral leishmaniasis
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985Twenty Kenyan patients with visceral leishmaniasis were evaluated for the presence of Leishmania donovani in their peripheral blood. Smears, cultures and hamster inoculations detected parasitaemia in 11, 10 and six patients, respectively, and at least one method detected parasitaemia in 15 patients (75%).
Chulay, JD, Adoyo, MA, Githure, JI
openaire +2 more sources
Karyotype Analysis of Leishmania Donovani
1989Kinetoplastid protozoa of the genus Leishmania are the causative agents of leishmaniasis which has recently been estimated to affect 20 million people, mainly in developing countries (Barker, 1987). A number of biochemical techniques have been applied to differentiate the organisms causing the various clinical forms of the disease, the most successful ...
Richard P. Bishop, Michael A. Miles
openaire +1 more source