Results 231 to 240 of about 35,225 (252)
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Glucose transport in Leishmania donovani promastigotes

Molecular and Biochemical Parasitology, 1984
Mid-log phase Leishmania donovani promastigotes accumulated 2-deoxy-D-glucose (2-DOG) via a carrier mediated transport system, maintaining an apparent Km of 24.4 microM and a Vmax of 3.12 nmol mg-1 protein min-1. D-Glucose but not L-glucose competitively inhibited the 2-DOG transport with an apparent Ki of 18.7 microM.
D, Zilberstein, D M, Dwyer
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Leishmania (Leishmania) donovani subsp. would Nicolle 1908

2020
Leishmania (Leishmania) donovani(Laveran et Mesnil, 1903) The record of L. donovani ZMON- 31 in Oman leads us to briefly discuss the taxonomic status and the geographical distribution of this zymodeme and closely related zymodemes. Starting in the 1980s, enzymatic taxonomy studies led to consider the linnean taxa L. donovani and L.
Rioux, Jean-Antoine   +4 more
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Chromosome size polymorphisms of Leishmania donovani

Molecular and Biochemical Parasitology, 1987
A minimum of 22 chromosomes were found in all Leishmania donovani stocks examined by orthogonal field alternation gel electrophoresis (OFAGE). Chromosome sizes ranged from approximately 270 to 4000 kb. Certain chromosomes were polymorphic in size between stocks and chromosomes present in some stocks had no apparent equivalent in others.
R P, Bishop, M A, Miles
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Leishmania donovani (Ross 1903)

1995
Visceral leishmaniasis, also known as kala-azar, has a wide distribution; no accurate estimate of its prevalence is currently available. The protozoan species that causes visceral leishmaniasis varies according to geographic regions; each has its own unique sandfly vectors and resevoir hosts.1 In India, Bangladesh, Nepal, and China the infection is ...
Dickson D. Despommier   +2 more
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In Vitro Tryptophan Catabolism by Leishmania donovani donovani Promastigotes

The Journal of Protozoology, 1992
ABSTRACT. Metabolism of tryptophan by promastigotes of Leishmania donovani donovani was investigated in cells suspended in a simple buffer solution supplemented with glucose. Metabolites from supernatant and lysed cell pellets were analyzed by capillary gas liquid chromatography and 13C nuclear magnetic resonance spectroscopy, with structural ...
S, Leelayoova   +4 more
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Characterization of strains of Leishmania donovani

Experimental Parasitology, 1966
Abstract Even with the most standardized procedures yet available for in vivo trials, the intrastrain variations in the course of infection of Leishmania donovani in the hamster permit no easy assessment of variations among those tested by us from several parts of the world.
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Oxidation of Leucine by Leishmania donovani

The Journal of Protozoology, 1991
ABSTRACT. The metabolism of leucine by Leishmania donovani was investigated. Washed promastigotes were incubated with (1‐14C]‐or [U‐14C]leucine or [1 ‐14C]α‐ketoisocaproate (KIC) and 14C02 release was measured. The amount of KIC‐derived acetyl‐CoA oxidized in the citric acid cycle was computed. Promastigotes from mid‐stationary phase cultures oxidized
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Leishmania donovani Tryparedoxin Peroxidase

2004
Leishmanien sind intrazelluläre Parasiten, die für die Krankheit Leishmaniasis verantwortlich sind. Die Suche nach Therapieansätzen ergab, dass der Trypanothione-vermittelte Hydroperoxide-Metabolismus die "Achilles-Sehne" dieser Trypanosomatiden ist, da sie dem Angriff von ROS (Reactive Oxyzen Species) ausgesetzt sind, die dem aeroben Stoffwechsel des ...
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Macromolecular Synthesis in Leishmania donovani Amastigotes

The Journal of Parasitology, 1985
Amastigotes (non-flagellated tissue forms) of Leishmania sp. reside and multiply within the phagolysosomes in tissue macrophages of vertebrate hosts. They are true obligate, intracellular parasites and do not persist as viable entities outside of host cells.
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Cellular Immunity to Leishmania Donovani

The Journal of Immunology, 1974
Abstract C57BL/6J mice were subjected to various combinations of immunosuppressive treatments and infected i.v. with amastigotes of Leishmania donovani. In normal mice the parasite population reached its peak about 24 days post-infection, after which parasite numbers gradually declined but they were still detectable on day 60. The course
Clare B Skov, Donald W Twohy
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