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Identification of adipocytes as target cells for Leishmania infantum parasites
Leishmania infantum is the causative agent of visceral leishmaniasis transmitted by the bite of female sand flies. According to the WHO, the estimated annual incidence of leishmaniasis is one million new cases, resulting in 30,000 deaths per year.
Aurélie Schwing+9 more
doaj +2 more sources
A novel A2 allele found in Leishmania (Leishmania) infantum chagasi [PDF]
Visceral leishmaniasis (VL) is a widely spread zoonotic disease. In Brazil the disease is caused by Leishmania (Leishmania) infantum chagasi. Peridomestic sandflies acquire the etiological agent by feeding on blood of infected reservoir animals, such as dogs or wildlife.
Oliveira, Trícia Maria Ferreira de Sousa+7 more
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Transmission of Leishmania infantum from cats to dogs [PDF]
Abstract Leishmania infantum infection in cats has been reported in several countries, including Brazil. However, the transmission of visceral leishmaniasis (VL) from cats to another host has not been proven yet. Therefore, the aim of this study was to verify the possibility of L. infantum transmission from cats to dogs.
Joilson Ferreira Batista+5 more
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Leishmania infantum in the reproductive organs of dogs [PDF]
ABSTRACT: Leishmania infantum causes canine leishmaniasis. Using parasitological and molecular analyses, we identified L. infantum in the reproductive organs of male and female dogs. Using histochemistry, immunohistochemistry, and PCR, we examined tissue samples from the reproductive organs of 8 male dogs and 16 female dogs diagnosed with leishmaniasis.
Diogo Tiago da Silva+9 more
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Genes and Chromosomes of Leishmania infantum [PDF]
During recent years, several Leishmania infantum genes have been cloned and characterized. Here, we have summarized the available information on the gene organization and expression in this protozoan parasite. From a comparative analysis, the following outstanding features were found to be common to most of the genes characterized: tandemly organized ...
María Requena, Jose+3 more
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Leishmania infantum in US-Born Dog [PDF]
Leishmaniasis is a vectorborne disease that can infect humans, dogs, and other mammals. We identified one of its causative agents, Leishmania infantum, in a dog born in California, USA, demonstrating potential for autochthonous infections in this country. Our finding bolsters the need for improved leishmaniasis screening practices in the United States.
Dennis R Spann+2 more
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Study of ocular manifestations and humoral immune response in eyes of dogs with leishmaniasis
Background Ocular manifestations in dogs with leishmaniasis are frequent and complications in affected tissues can lead to blindness. Immune processes play a very important role in the pathogenesis of ocular inflammation.
Amel F. El Goulli+6 more
doaj +1 more source
Leishmania infantum, the sand fly-transmitted protozoan parasite responsible for leishmaniasis in humans, dogs, and cats, is endemic in the Iberian Peninsula. However, the impact of L. infantum infection on the conservation of the endangered Iberian lynx
Clara M. Lima+7 more
doaj +1 more source
Structures of the Leishmania infantum polymerase beta [PDF]
Protozoans of the genus Leishmania, the pathogenic agent causing leishmaniasis, encode the family X DNA polymerase Li Pol β. Here, we report the first crystal structures of Li Pol β. Our pre- and post-catalytic structures show that the polymerase adopts the common family X DNA polymerase fold. However, in contrast to other family X DNA polymerases, the
Mejía Edison+6 more
openaire +4 more sources
A Case of Leishmania Infantum Mimicking Lymphoma
Leishmaniasis is a parasitic infection caused by an obligate intracellular protozoon transmitted by infected sand flies. Cutaneous leishmaniasis (CL) is a skin disease known in our country as oriental sore, which heals, leaving a scar in place, mainly on the skin and sometimes in the mucous membrane.
Gulnaz Culha+3 more
openaire +2 more sources