Results 21 to 30 of about 79,414 (305)

Leishmania infantum in US-Born Dog [PDF]

Emerging Infectious Diseases, 2020
Leishmaniasis is a vectorborne disease that can infect humans, dogs, and other mammals. We identified one of its causative agents, Leishmania infantum, in a dog born in California, USA, demonstrating potential for autochthonous infections in this country. Our finding bolsters the need for improved leishmaniasis screening practices in the United States.
Dennis R Spann, Marcos de Almeida, Richard S. Bradbury   +2 more
openaire   +4 more sources

Structures of the Leishmania infantum polymerase beta [PDF]

DNA Repair, 2014
Protozoans of the genus Leishmania, the pathogenic agent causing leishmaniasis, encode the family X DNA polymerase Li Pol β. Here, we report the first crystal structures of Li Pol β. Our pre- and post-catalytic structures show that the polymerase adopts the common family X DNA polymerase fold. However, in contrast to other family X DNA polymerases, the
Mejía Edison, Burak, Matthew, Alonso, Ana, Larraga, Vicente, Kunkel, Thomas A., Bebenek, Katarzyna, García-Díaz, Miguel   +6 more
openaire   +4 more sources

First molecular detection of Leishmania (Leishmania) infantum chagasi in a domestic cat (Felis catus) from an urban area in eastern Amazon [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2023
Background: Domestic cats have been implicated as accidental hosts of Leishmania sp. However, in recent years, the recurrent description of new cases in endemic and nonendemic areas draw attention to the potential epidemiological role of cats as ...
Délia Cristina Figueira Aguiar, Daniela de Nazaré dos Santos Nascimento, Dinaiara Fragoso Penner, Brena do Socorro Lima de Castro, Rodrigo Rodrigues Virgolino, Alan Marcel Pamplona Neves, Andrei dos Santos Siqueira, Evonnildo Costa Gonçalves   +7 more
doaj   +1 more source

New diarylsulfonamide inhibitors of Leishmania infantum amastigotes

International Journal for Parasitology: Drugs and Drug Resistance, 2021
New drugs against visceral leishmaniasis with mechanisms of action differing from existing treatments and with adequate cost, stability, and properties are urgently needed. No antitubulin drug is currently in the clinic against Leishmania infantum, the causative agent of visceral leishmaniasis in the Mediterranean area. We have designed and synthesized
Myriam González, Pedro José Alcolea, Raquel Álvarez, Manuel Medarde, Vicente Larraga, Rafael Peláez   +5 more
openaire   +6 more sources

Genetic Diversity and Population Structure of Leishmania infantum in Morocco as Revealed by Multilocus Sequence Typing (MLST) Approach

Pathogens, 2023
Leishmania infantum is endemic in Morocco, and it causes both visceral (VL) and cutaneous leishmaniasis (CL). In this study, the multilocus sequence typing (MLST) approach was used to investigate the phylogeny and population structure of Leishmania ...
Sara El Mazini, Mourad Barhoumi, Idris Mhaidi, Othmane Daoui, Mouad Ait Kbaich, Sofia El Kacem, Imane El idrissi Saik, Myriam Riyad, Khadija Bekhti, Ikram Guizani, Meryem Lemrani   +10 more
doaj   +1 more source

Treatment of <i>Leishmania infantum</i> Infections in Dogs. [PDF]

Microorganisms
Dogs are reservoir hosts of the zoonotic parasite Leishmania infantum, the causative agent of canine leishmaniosis. Antiparasitic drugs that are commonly used in dogs include allopurinol, miltefosine, and meglumine antimoniate. Treatment success is characterized by an improvement of disease signs, reduction in parasite load, as well as prevention of ...
Kaempfle M, Hartmann K, Bergmann M.
europepmc   +3 more sources

Leishmania infantum and Dirofilaria immitis infections in Italy, 2009–2019: changing distribution patterns

Parasites & Vectors, 2020
For long time, canine leishmaniosis (CanL) was considered endemic in the southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by Dirofilaria immitis was considered endemic in the northern region and in the swampy Po ...
J. Mendoza-Roldan, G. Benelli, R. Panarese, R. Iatta, T. Furlanello, F. Beugnet, A. Zatelli, D. Otranto   +7 more
semanticscholar   +1 more source

The study of cells using scanning force microscopy [PDF]

, 2011
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Eley, AR, Garcia, ALM, Geoghegan, M, Hall, AR, Rogers, ME, Rolfe, SA   +5 more
core   +7 more sources

Development of a LAMP assay for detection of Leishmania infantum infection in dogs using conjunctival swab samples [PDF]

, 2015
Background: Leishmania infantum infections in dogs play a crucial role in the transmission of pathogens causing visceral leishmaniasis to humans in the Gansu province, northwest China. To be able to control zoonotic transmission of the parasite to humans,
A Moshfe, A Nasereddin, AF Koutinas, CH Gao, Chun-hua Gao, D Otranto, D Strauss-Ayali, Dan Ding, Dietmar Steverding, ER Adams, F Dantas-Torres, Feng Shi, G Schönian, H Kaneko, H Takagi, J Alvar, J Dereure, JM Lawrie, Jun-yun Wang, JY Wang, JY Wang, JY Wang, K Stuart, L Chamaillé, L He, L Solano-Gallego, LL Poon, LS Leontides, M Chaouch, M Gramiccia, M Paiva Cavalcanti de, MG Khan, N Chargui, N Kuboki, N Singh, P Ciaramella, RS Leite, S Reale, SA Ferreira, T Muccio Di, T Notomi, UG Lopes, WP Kennedy, X Ni, Xia Wang, Y Fichoux le, Y Mori, YM Gomes, Yue-tao Yang   +48 more
core   +1 more source

Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal [PDF]

, 2013
The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s.
Afonso, Maria Odete, Campino, Lenea, Cristovao, Jose Manuel, Dionisio, Lidia, Maia, Carla, Neto, Luis   +5 more
core   +7 more sources