Results 21 to 30 of about 59,567 (270)
Structures of the Leishmania infantum polymerase beta [PDF]
DNA Repair, 2014 Protozoans of the genus Leishmania, the pathogenic agent causing leishmaniasis, encode the family X DNA polymerase Li Pol β. Here, we report the first crystal structures of Li Pol β. Our pre- and post-catalytic structures show that the polymerase adopts the common family X DNA polymerase fold. However, in contrast to other family X DNA polymerases, the
Mejía Edison +6 more
openaire +4 more sources
Parasites & Vectors, 2020 For long time, canine leishmaniosis (CanL) was considered endemic in the southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by Dirofilaria immitis was considered endemic in the northern region and in the swampy Po ...
J. Mendoza-Roldan +7 more
semanticscholar +1 more source
A Case of Leishmania Infantum Mimicking Lymphoma
Indian Journal of Dermatology, 2023 Leishmaniasis is a parasitic infection caused by an obligate intracellular protozoon transmitted by infected sand flies. Cutaneous leishmaniasis (CL) is a skin disease known in our country as oriental sore, which heals, leaving a scar in place, mainly on the skin and sometimes in the mucous membrane.
Gulnaz Culha +3 more
openaire +2 more sources
Pathogens, 2023 Leishmania infantum is endemic in Morocco, and it causes both visceral (VL) and cutaneous leishmaniasis (CL). In this study, the multilocus sequence typing (MLST) approach was used to investigate the phylogeny and population structure of Leishmania ...
Sara El Mazini +10 more
doaj +1 more source
First molecular detection of Leishmania (Leishmania) infantum chagasi in a domestic cat (Felis catus) from an urban area in eastern Amazon [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2023 Background: Domestic cats have been implicated as accidental hosts of Leishmania sp. However, in recent years, the recurrent description of new cases in endemic and nonendemic areas draw attention to the potential epidemiological role of cats as ...
Délia Cristina Figueira Aguiar +7 more
doaj +1 more source
New diarylsulfonamide inhibitors of Leishmania infantum amastigotes
International Journal for Parasitology: Drugs and Drug Resistance, 2021 New drugs against visceral leishmaniasis with mechanisms of action differing from existing treatments and with adequate cost, stability, and properties are urgently needed. No antitubulin drug is currently in the clinic against Leishmania infantum, the causative agent of visceral leishmaniasis in the Mediterranean area. We have designed and synthesized
Myriam González +5 more
openaire +6 more sources
Revista da Sociedade Brasileira de Medicina Tropical, 2011 INTRODUÇÃO: O município de Jaciara foi classificado em 2003, como área de transmissão de leishmaniose visceral em situação de surto. O trabalho objetivou determinar evidência de transmissão de Leishmania (Leishmania) infantum chagasi por Lutzomyia cruzi ...
Nanci Akemi Missawa +4 more
doaj +1 more source
NEW PRIMERS FOR DETECTION OF Leishmania infantum USING POLYMERASE CHAIN REACTION
Revista do Instituto de Medicina Tropical de São Paulo, 2015 SUMMARY Leishmania infantum causes visceral leishmaniasis (VL) in the New World. The diagnosis of VL is confirmed by parasitological and serological tests, which are not always sensitive or specific.
Kézia Peres GUALDA +6 more
doaj +1 more source
PLoS Neglected Tropical Diseases, 2020 Leishmaniasis constitutes the 9th largest disease burden among all infectious diseases. Control of this disease is based on a short list of chemotherapeutic agents headed by pentavalent antimonials, followed by miltefosine and amphotericin B; drugs that ...
Noélie Douanne +4 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 Human infection with different species of Leishmania leads to distinct clinical manifestations, ranging from relatively mild cutaneous (Leishmania braziliensis) to severe visceral (Leishmania infantum) forms of leishmaniasis.
Agostinho Gonçalves Viana +7 more
doaj +1 more source