Results 21 to 30 of about 78,367 (315)

A cross-sectional study of Leishmania infantum infection in stray cats in the city of Zaragoza (Spain) using serology and PCR

Parasites & Vectors, 2021
Background Feline leishmaniosis is a vector-borne parasitic disease caused by Leishmania spp. Leishmania infection in dogs is prevalent in the Mediterranean basin, but in other animals, such as cats, it could also play a role in the epidemiology of the ...
M. Alcover, A. Basurco, Antonio Fernández, C. Riera, R. Fisa, Ana González, M. Verde, A. Garrido, H. Ruíz, Andrés Yzuel, S. Villanueva‐Saz   +10 more
semanticscholar   +1 more source

Identification of Chalcone Derivatives as Inhibitors of Leishmania infantum Arginase and Promising Antileishmanial Agents

Frontiers in Chemistry, 2021
Arginase catalyzes the hydrolysis of l-arginine into l-ornithine and urea, acting as a key enzyme in the biosynthesis of polyamines. Leishmania growth and survival is dependent on polyamine biosynthesis; therefore, inhibition of Leishmania arginase may ...
Andreza R Garcia, D. Oliveira, J. B. Jesus, Alessandra M T Souza, A. C. Sodero, Alane Beatriz Vermelho, I. Leal, Rodrigo Octavio Mendonça Alves Souza, L. S. Miranda, A. Pinheiro, I. A. Rodrigues   +10 more
semanticscholar   +1 more source

Colonization and genetic diversification processes of Leishmania infantum in the Americas

Communications Biology, 2021
Leishmania infantum causes visceral leishmaniasis, a deadly vector-borne disease introduced to the Americas during the colonial era. This non-native trypanosomatid parasite has since established widespread transmission cycles using alternative vectors ...
P. Schwabl, M. Boité, G. Bussotti, A. Jacobs, B. Andersson, O. Moreira, A. L. Freitas-Mesquita, J. Meyer‐Fernandes, E. Telleria, Y. Traub-Csekö, S. Vaselek, T. Lestinova, P. Volf, F. Morgado, R. Porrozzi, M. Llewellyn, G. Späth, E. Cupolillo   +17 more
semanticscholar   +1 more source

Detection of Leishmania tarentolae in lizards, sand flies and dogs in southern Italy, where Leishmania infantum is endemic: hindrances and opportunities

Parasites & Vectors, 2021
Background Leishmania tarentolae is a protozoan isolated from geckoes ( Tarentola annularis , Tarentola mauritanica ), which is considered non-pathogenic and is transmitted by herpetophilic Sergentomyia spp. sand flies.
J. Mendoza-Roldan, M. Latrofa, R. Iatta, Ranju R. S. Manoj, R. Panarese, G. Annoscia, M. Pombi, A. Zatelli, F. Beugnet, D. Otranto   +9 more
semanticscholar   +1 more source

Leishmania manipulation of sand fly feeding behavior results in enhanced transmission. [PDF]

, 2007
In nature the prevalence of Leishmania infection in whole sand fly populations can be very low (
Bates, Paul A, Rogers, Matthew E
core   +7 more sources

Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal [PDF]

, 2013
The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s.
Afonso, Maria Odete, Campino, Lenea, Cristovao, Jose Manuel, Dionisio, Lidia, Maia, Carla, Neto, Luis   +5 more
core   +7 more sources

New diarylsulfonamide inhibitors of Leishmania infantum amastigotes

International Journal for Parasitology: Drugs and Drug Resistance, 2021
New drugs against visceral leishmaniasis with mechanisms of action differing from existing treatments and with adequate cost, stability, and properties are urgently needed. No antitubulin drug is currently in the clinic against Leishmania infantum, the causative agent of visceral leishmaniasis in the Mediterranean area. We have designed and synthesized
Myriam González, Pedro José Alcolea, Raquel Álvarez, Manuel Medarde, Vicente Larraga, Rafael Peláez   +5 more
openaire   +6 more sources

Genetic Diversity and Population Structure of Leishmania infantum in Morocco as Revealed by Multilocus Sequence Typing (MLST) Approach

Pathogens, 2023
Leishmania infantum is endemic in Morocco, and it causes both visceral (VL) and cutaneous leishmaniasis (CL). In this study, the multilocus sequence typing (MLST) approach was used to investigate the phylogeny and population structure of Leishmania ...
Sara El Mazini, Mourad Barhoumi, Idris Mhaidi, Othmane Daoui, Mouad Ait Kbaich, Sofia El Kacem, Imane El idrissi Saik, Myriam Riyad, Khadija Bekhti, Ikram Guizani, Meryem Lemrani   +10 more
doaj   +1 more source

First molecular detection of Leishmania (Leishmania) infantum chagasi in a domestic cat (Felis catus) from an urban area in eastern Amazon [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2023
Background: Domestic cats have been implicated as accidental hosts of Leishmania sp. However, in recent years, the recurrent description of new cases in endemic and nonendemic areas draw attention to the potential epidemiological role of cats as ...
Délia Cristina Figueira Aguiar, Daniela de Nazaré dos Santos Nascimento, Dinaiara Fragoso Penner, Brena do Socorro Lima de Castro, Rodrigo Rodrigues Virgolino, Alan Marcel Pamplona Neves, Andrei dos Santos Siqueira, Evonnildo Costa Gonçalves   +7 more
doaj   +1 more source

Leishmania infantum and Dirofilaria immitis infections in Italy, 2009–2019: changing distribution patterns

Parasites & Vectors, 2020
For long time, canine leishmaniosis (CanL) was considered endemic in the southern, central, and insular regions of Italy, whereas heartworm disease (HW) caused by Dirofilaria immitis was considered endemic in the northern region and in the swampy Po ...
J. Mendoza-Roldan, G. Benelli, R. Panarese, R. Iatta, T. Furlanello, F. Beugnet, A. Zatelli, D. Otranto   +7 more
semanticscholar   +1 more source