BackgroundNucleosomal histones are intracellular proteins that are highly conserved among Leishmania species. After parasite destruction or spontaneous lysis, exposure to these proteins elicits a strong host immune response.
Marcia W Carneiro +9 more
doaj +1 more source
Pet and Stray Dogs’ Contribution to Zoonotic Transmission Pathways: A Bibliometric Review
Based on a large‐scale bibliometric dataset, domestic dogs (Canis lupus familiaris) emerge as the most frequently cited host species in the context of zoonoses, being mentioned in at least 10% of publications for nearly a quarter of the pathogens recognized as zoonotic to humans.
Thibaut Langlois +3 more
wiley +1 more source
Successful isolation of Leishmania infantum from Rhipicephalus sanguineus sensu lato (Acari : Ixodidae) collected from naturally infected dogs [PDF]
Background: The main transmission route of Leishmania infantum is through the bites of sand flies. However, alternative mechanisms are being investigated, such as through the bites of ticks, which could have epidemiological relevance.
Araújo, Nadjar Nitz Silva Lociks de +9 more
core +2 more sources
On the PhyloQuant protein expression profiles approach to the taxonomic problem
Abstract Inferring evolutionary relationships among organisms has been a fundamental problem in evolutionary biology. The current phylogenetic molecular methods serve as the baseline model to test new evolutionary hypotheses with taxonomic purposes. Leishmaniinae trypanosomatids subfamily includes protozoan parasites of clinical importance to humans ...
Ayixon Sánchez Reyes +1 more
wiley +1 more source
The clinical-immunological spectrum of human Leishmania (L.) infantum chagasi-infection in Amazonian Brazil has recently been reviewed based on the combined use of the delayed-type hypersensitivity (DTH) and indirect fluorescence antibody test (IFAT-IgG ...
Luciana Lima +8 more
doaj +1 more source
Cutaneous leishmaniasis is of particular importance in southern Iran. This study aimed to investigate the infection of rodents with Leishmania major in an urban area of Fars Province, located in southern Iran. Rodents were trapped and samples from the liver, spleen, and skin were collected.
Saeed Shahabi +4 more
wiley +1 more source
Risk factors for visceral leishmaniasis in a new epidemic site in Amhara Region, Ethiopia [PDF]
We conducted a case-control study to evaluate risk factors for visceral leishmaniasis during an epidemic in a previously unaffected district of Ethiopia. We also collected blood and bone marrow specimens from dogs in the outbreak villages.
Alvar, Jorge +11 more
core +1 more source
Quercetin as a Promising Antiprotozoan Phytochemical: Current Knowledge and Future Research Avenues
Despite tremendous advances in the prevention and treatment of infectious diseases, only few antiparasitic drugs have been developed to date. Protozoan infections such as malaria, leishmaniasis, and trypanosomiasis continue to exact an enormous toll on public health worldwide, underscoring the need to discover novel antiprotozoan drugs. Recently, there
Hamed Memariani +3 more
wiley +1 more source
Identification of Leishmania species by high-resolution DNA dissociation in cases of American cutaneous leishmaniasis, [PDF]
Background American cutaneous leishmaniasis is an infectious dermatosis caused by protozoa of the genus Leishmania, which comprises a broad spectrum of clinical manifestations depending on the parasite species involved in the infections and the ...
John Verrinder Veasey +4 more
doaj +2 more sources
A Leishmania-specific hypothetical protein expressed in both promastigote and amastigote stages of Leishmania infantum employed for the serodiagnosis of, and as a vaccine candidate against, visceral leishmaniasis [PDF]
Background: LiHyV is an antigenic hypothetical protein present in both promastigote and amastigote stages of Leishmania infantum, which was recently identified by an immunoproteomic approach.
Chávez-Fumagalli, Miguel A. +9 more
core +3 more sources

