Results 61 to 70 of about 44,587 (226)

Glycosomal Phosphoenolpyruvate Carboxykinase CRISPR/Cas9‐Deletion and Its Role in Trypanosoma cruzi Metacyclogenesis and Infectivity in Mammalian Host

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Effects of PEPCK deficiency in Trypanosoma cruzi bioenergetics and life stages. ABSTRACT Trypanosoma cruzi, the causative agent of Chagas disease, possesses glycosomes—unique organelles that house key metabolic enzymes, several of which are promising therapeutic targets.
Carolina S. D. Vieira, Wei Wang, Fernando Sanchez‐Valdez, Jihyun Lim, Brooke E. White, Camilla G. S. Souza, Rick L. Tarleton, Marcia C. Paes, Natalia P. A. Nogueira   +8 more
wiley   +1 more source

Leishmania infection in humans, dogs and sandflies in a visceral leishmaniasis endemic area in Maranhão, Brazil

Memorias do Instituto Oswaldo Cruz, 2011
Leishmania infection in humans, dogs and sandflies was examined in the endemic visceral leishmaniasis (VL) municipality of Raposa, state of Maranhão, Brazil.
Ilana Mirian Almeida Felipe, Dorlene Maria Cardoso de Aquino, Oliver Kuppinger, Max Diego Cruz Santos, Maurício Eduardo Salgado Rangel, David Soeiro Barbosa, Aldina Barral, Guilherme Loureiro Werneck, Arlene de Jesus Mendes Caldas   +8 more
doaj   +1 more source

Oxidative costs of migration: infections as an added burden

Journal of Avian Biology, Volume 2026, Issue 2, March 2026.
There is increasing evidence that over‐production of reactive species (RS) constitutes a significant physiological cost for migrating birds. The current view entails that RS during migration originate primarily from increased metabolic activity associated with prolonged flights and refueling.
Michael Tobler, Dennis Hasselquist, Arne Hegemann, Lucía Jiménez‐ Gallardo, Javier Pérez‐ Tris, Carolina Remacha   +5 more
wiley   +1 more source

Analysis by RNA-seq of transcriptomic changes elicited by heat shock in Leishmania major [PDF]

, 2019
Besides their medical relevance, Leishmania is an adequate model for studying post-transcriptional mechanisms of gene expression. In this microorganism, mRNA degradation/stabilization mechanisms together with translational control and post-translational ...
Aguado, Begoña, Corvo, Laura, Lombraña, Rodrigo, Rastrojo, Alberto, Requena, Jose M., Solana, Jose C.   +5 more
core   +2 more sources

Artificial intelligence strategies for predicting kinase inhibitor resistance: A comprehensive review of methods, challenges, and future perspectives

Journal of Intelligent Medicine, Volume 3, Issue 1, Page 26-46, March 2026.
Abstract Kinase inhibitors are essential in targeted cancer therapy, yet resistance often emerges through secondary mutations, activation of compensatory signaling pathways, or drug‐efflux mechanisms. Artificial intelligence (AI) provides a workflow‐based strategy rather than a list of unrelated tools for predicting and addressing kinase‐inhibitor ...
Faris Hassan, Mohanad Ali Deifallah, Alaa Zaghloul, Rania Elgohary   +3 more
wiley   +1 more source

Evaluation of the presence of Leishmania infantum in bone stored in glycerol or sterilized by autoclave for cortical bone grafting

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
This study was performed to evaluate the effects of autoclaving and storage in 85% glycerol on cortical bone from dogs infected with Leishmania sp. We used 42 cadavers with leishmaniasis. The dogs were evaluated for the presence of Leishmania sp.
M.A.M. Lopes, S.O. Silva, I.F.G. Amorim, W.L. Tafuri, M.N. Melo, C.M.F. Rezende   +5 more
doaj   +1 more source

Leishmania spp. parasite isolation through inoculation of patient biopsy macerates in interferon gamma knockout mice Leishmania spp.: isolamento de parasitos pela inoculação de macerados de biopsias de pacientes em camundongos deficientes em interferon gama

Revista do Instituto de Medicina Tropical de São Paulo, 2010
Isolation of Leishmania parasite and species identification are important for confirmation and to help define the epidemiology of the leishmaniasis. Mice are often used to isolate pathogens, but the most common mouse strains are resistant to infection ...
Milton Adriano Pelli de Oliveira, Alause da Silva Pires, Rosidete Pereira de Bastos, Glória Maria Collet de Araujo Lima, Sebastião Alves Pinto, Ledice Inácia de Araujo Pereira, Ana Joaquina Cohen Serique Pereira, Ises de Almeida Abrahamsohn, Miriam Leandro Dorta, Fátima Ribeiro-Dias   +9 more
doaj   +1 more source

HYSTOPATHOLOGY AND Leishmania sp. IMMUNOSTAINING IN THIRD EYELID OF Leishmania (Leishmania) chagasi NATURALLY INFECTED DOGS

Ciência Animal Brasileira, 2015
A leishmaniose visceral canina (LVC) é uma doença que envolve lesões multissistêmicas e, dentre osvários tecidos acometidos, a terceira pálpebra está frequentemente envolvida. Este anexo ocular temsido alvo de estudo tanto para a elucidação da patogênese da doença quanto para o avanço diagnóstico.O presente trabalho teve por objetivo avaliar as ...
Lima, Aline Maria Vasconcelos, Santos, Adriana da Silva, Faleiro, Mariana Batista Rodrigues, Moura, Veridiana Maria Brianezi Dignani de, Brito, Fábio Luiz da Cunha, Brito, Luiz Augusto Batista   +5 more
openaire   +2 more sources

Molecular Detection and Genetic Diversity of Bat‐Associated Bartonella spp. in Bat Ectoparasites Collected From Ratchaburi Province, Thailand

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Bat ectoparasites collected from four insectivorous bat species were identified through mitochondrial gene analysis. This study provides the first evidence of bat‐associated Bartonella species in ectoparasites, including bat flies (Phthiridium sp., Raymondia sp.
Sakone Sunantaraporn, Supaporn Wacharapluesadee, Patarapol Maneeorn, Chatuthanai Savigamin, Luke W. Rimmer, Nitis Rattanagitpaisan, Thanapat Pataradool, Rungfar Boonserm, Somchai Panphuangkaew, Prateep Duenkae, Padet Siriyasatien   +10 more
wiley   +1 more source

Evaluation of antigens for the serodiagnosis of kala-azar and oriental sores by means of the indirect immunofluorescence antibody test (IFAT) [PDF]

, 1981
Antigens and corresponding sera were collected from travellers with leishmaniasis returning to Germany from different endemic areas of the old world. The antigenicity of these Leishmania strains, which were maintained in Syrian hamsters, was compared by ...
A. Zuckermann, E. C. Hedge, E. Mannweiler, F. Falkner v. Sonnenburg, G. Piekarski, G. Weiland, Gh. H. Endrissian, H. E. Krampitz, H. E. Krampitz, H. E. Krampitz, J. J. Shaw, J. Ranque, L. Prüfer, M. Lopez-Brea, N. Beforouz, R. S. Bray, R. S. Bray, R. S. Bray, T. I. Aljeboori, Th. Löscher   +19 more
core   +1 more source