Results 91 to 100 of about 2,272 (172)

Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response

, 2012
Background: Leishmania (L.) species are the causative agent of leishmaniasis. Due to the lack of efficient vaccine candidates, drug therapies are the only option to deal with cutaneous leishmaniasis.
Uwe Ritter (130470), Schmid, Maximilian, Hanses Frank, Ulrike Schleicher (104689), Frank Hanses, Maximilian Schmid, Florian, Christian, Frank Hanses (148604), Zimara Nicole, Wolfgang Ernst (13060), Wege, Anja Kathrin, Anja Kathrin Wege, Anja Kathrin Wege (148586), Christian Florian, Ernst, Wolfgang, Uwe Ritter, Hanses, Frank, Maximilian Schmid (148609), Florian Christian, Ritter Uwe, Nicole Zimara (148595), Zimara, Nicole, Christian Florian (148590), Schleicher, Ulrike, Ritter, Uwe, Nicole Zimara, Ernst Wolfgang, Schmid Maximilian, Schleicher Ulrike, Wege Anja Kathrin, Wolfgang Ernst, Ulrike Schleicher   +31 more
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Comparison of Cysteine Protease B Gene Expression between Clinical Isolates of Leishmania tropica, Leishmania major and Leishmania infantum

Journal of Medical Microbiology and Infectious Diseases, 2019
Introduction: Leishmania cysteine protease B (CPB) is a parasite virulence factor that plays a vital role in host-parasitic interactions. Regarding the importance of the CPB gene, we used a quantitative real-time RT-PCR to investigate the expression of ...
Elham Kazemirad, Hossien Reisi Nafchi, Alireza Latifi, Reza Raoofian, Mehdi Mohebali, Homa Hajjaran   +5 more
doaj  

Development of a multilocus microsatellite typing approach for discriminating strains of Leishmania (Viannia) species.

, 2009
A multilocus microsatellite typing (MLMT) approach based on the analysis of 15 independent loci has been developed for the discrimination of strains belonging to different Viannia species.
Espinosa, Diego, Oddone, Rolando, Arevalo, Jorge, Mauricio, Isabel, Schweynoch, Carola, Sousa, Cintia dos Santos de, Kuhls, Katrin, de Sousa, Cintia dos Santos, Cupolillo, Elisa, Schönian, Gabriele, Noyes, Harry   +10 more
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Cutaneous leishmaniasis infection in Balb/c mice using a Leishmania tropica strain isolated from Turkey

, 2001
Leishmania tropica, which is endemic in Turkey, is the causative agent of cutaneous leishmaniasis. Leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in NNN medium were inoculated subcutaneously ...
Ozbilgin, A, Ozbel, Y, Yereli, K, Balcioglu, IC, Girginkardesler, N   +4 more
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"DIFERENTIAION OF LEISHMANIA TROPICA MAJOR FROM LEISHMANIA TROPICA MINOR BY INOCULATION TO LABORATORY ANIMALS "

Iranian Journal of Public Health, 1973
The subcutaneous inoculation of 16 white mice and 10 golden hamsters with L.tropica major resulted in the development of leishmanial lesions in all, becoming generalized in some.Two of 10 hamsters inoculated intraperitoneally with this parasite developed generalized lesions. On the other hand, the inoculation of L.
A.Nadim, Gh.Tahvildar-Bidruni, M.Farshian, AA.Heydari-Mohammad Abadi   +3 more
openaire   +2 more sources

Synthesis of thiosemicarbazone Schiff base derivatives as anti-leishmanial agents and molecular dynamics simulations insights

Scientific Reports
Leishmaniasis is one of the infectious diseases caused by protozoa and is considered the second most significant parasitic disease after malaria. In this research, thiosemicarbazone Schiff base derivatives were synthesized via a one-pot, two-step, three ...
Soheila Molaei, Jafar Abbasi Shiran, Neda Shakour, Majid Baradaran, Zahra Malihi, Mohammad Reza Rahimi, Yasamin Abedini Zal, Saghi Sepehri   +7 more
doaj   +1 more source

Domestic dog ownership: a risk factor for human infection with Leishmania (Viannia) species.

, 2003
An epidemiological study has shown that cumulative, village prevalence of Leishmania (Viannia) infection in dogs ranges from 8% to 45% in Huánuco, Peru. Using data from a prospective survey of human American cutaneous leishmaniasis (ACL) collected during
Reithinger, Richard, Llanos-Cuentas, Alejandro, Canales Espinoza, Juan, Davies, Clive R   +3 more
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Infecção natural por Leishmania sp. em flebotomíneos capturados no foco de transmissão de Leishmaniose Tegumentar Americana no município de Piçarras, litoral norte do Estado de Santa Catarina e identificação específica do parasito em amostras clínicas e em cepas isoladas de pacientes. [PDF]

, 2008
TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.As Leishmanioses são doenças infecto-parasitárias causadas por protozoários do gênero Leishmania, que acometem cerca de 12 milhões de indivíduos em 88 países
Bittencourt, Ize de Aguiar
core  

Identification of Leishmania tropica and Leishmania aethiopica by DNA sequencing and the detection of Leishmania RNA Virus [PDF]

, 2018
Leishmaniasis is a neglected tropical disease and a major cause of morbidity and mortality in impoverished countries. Leishmaniasis is a global disease and is clinically and epidemiologically diverse, with many different species of Leishmania affecting ...
Bates, Paul, Thomas, Megan
core  

Genomic Characterization of Leishmania tropica in Cutaneous Leishmaniasis, Somali Region, Ethiopia, 2023

Emerging Infectious Diseases
We sequenced Leishmania tropica genomes from 8 human skin samples collected in a newly emerging focus of cutaneous leishmaniasis in the Somali region of Ethiopia. We found a variant with unique genomic signatures of drug resistance.
Adugna Abera, Pieter Monsieurs, Myrthe Pareyn, Dereje Beyene, Geremew Tasew, Allison Aroni-Soto, Mahlet Belachew, Desalegn Geleta, Bethlehem Adnew, Bokretsion Gidey, Henok Tadesse, Atsbeha Gebreegziabxier, Rajiha Abubeker, Abraham Ali, Ketema Tafess, Tobias F. Rinke de Wit, Johan van Griensven, Jean-Claude Dujardin, Dawit Wolday, Malgorzata Anna Domagalska   +19 more
doaj   +1 more source