Antileishmanial Activity and Inducible Nitric Oxide Synthase Activation by RuNO Complex
Parasites of the genus Leishmania are capable of inhibiting effector functions of macrophages. These parasites have developed the adaptive ability to escape host defenses; for example, they inactivate the NF‐κB complex and suppress iNOS expression in infected macrophages, which are responsible for the production of the major antileishmanial substance ...
Tatiane Marcusso Orsini +15 more
wiley +1 more source
Epidemiology of visceral leishmaniasis. [PDF]
Leishmania species are the causative agents of leishmaniasis, a neglected tropical disease. These parasitic protozoans are usually transmitted between vertebrate hosts by the bite of blood sucking female phlebotomine sand flies.
Ready, Paul D
core +3 more sources
The health industry has always used natural products as a rich, promising, and alternative source of drugs that are used in the health system. Propolis, a natural resinous product known for centuries, is a complex product obtained by honey bees from substances collected from parts of different plants, buds, and exudates in different geographic areas ...
Ricardo Silva-Carvalho +3 more
wiley +1 more source
Seroprevalence of feline leishmaniasis in Paraná using antigens from different species of Leishmania spp / Soroprevalência da leishmaniose felina no Paraná utilizando-se antígenos de diferentes espécies de Leishmania spp [PDF]
In domestic cats, the number of infections caused by parasites of the genus Leishmania is becoming increasingly significant, although the role of felines in this cycle is not yet clear.
Caldart, Eloiza Teles +7 more
core +1 more source
Some epidemiological aspects of leishmaniasis in the municipality of Formiga, Brazil, an important touristic site, were evaluated. Those included phlebotomine sand fly vectors, canine infection, and geoprocessing analysis for determining critical transmission areas. Sand flies (224 insects) belonging to ten different species were captured.
Júlia Alves Menezes +13 more
wiley +1 more source
Systemic Therapy of New World Cutaneous Leishmaniasis: A Case Report and Review Article
Cutaneous leishmaniasis is a disease endemic to Central and South America, Mexico and the Caribbean, and affects millions of people. As travel to these regions becomes more common, cutaneous leishmaniasis is becoming a disease of increasing importance in the developed world.
Amir Abadir, Ameen Patel, Shariq Haider
wiley +1 more source
In Vitro Evaluation of a Soluble Leishmania Promastigote Surface Antigen as a Potential Vaccine Candidate against Human Leishmaniasis [PDF]
International audiencePSA (Promastigote Surface Antigen) belongs to a family of membrane-bound and secreted proteins present in severalLeishmania (L.) species.
A Devault +85 more
core +7 more sources
Field ecology of sylvatic Rhodnius populations (Heteroptera, Triatominae): risk factors for palm tree infestation in western Ecuador. [PDF]
Most Rhodnius species (Triatominae) are primarily associated with palm trees. They maintain enzootic Trypanosoma cruzi transmission and are responsible for human infection (causing Chagas disease) through the Neotropics. Assessing whether individual palm
Ho, A. Y. Q. +5 more
core +4 more sources
Resumen La leishmaniasis tegumentaria en el estado Trujillo es una enfermedad endémica. Actualmente existe una alta incidencia, de 120 a 130 casos nuevos/año, procedentes de distintos sectores en la entidad, afectando a todos los grupos etários.
Espinoza, A., Rojas, E., Scorza, J. V
openaire +2 more sources
Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B. [PDF]
Disfiguring skin lesions caused by several species of the Leishmania parasite characterize cutaneous leishmaniasis (CL). Successful treatment of CL with intravenous (i.v.) liposomal amphotericin B (LAmB) relies on the presence of adequate antibiotic ...
Alavijeh, Mo +7 more
core +2 more sources

