Results 81 to 90 of about 335,692 (203)

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

open access: yesPhotochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza   +3 more
wiley   +1 more source

Cutaneous Manifestations of Human and Murine Leishmaniasis

open access: yesInternational Journal of Molecular Sciences, 2017
The leishmaniases are diseases caused by pathogenic protozoan parasites of the genus Leishmania. Infections are initiated when a sand fly vector inoculates Leishmania parasites into the skin of a mammalian host.
Breanna M. Scorza   +2 more
semanticscholar   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, EarlyView.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

Multilesional cutaneous leishmaniasis [PDF]

open access: yesCanadian Medical Association Journal, 2016
A 27-year-old healthy woman presented to the medical centre with a one-month history of widespread skin lesions with slow clinical progression. The lesions appeared on her thighs, shins, lower abdomen and left arm three weeks after she had travelled to an area endemic for Leishmania major ...
Yuval Ramot, Abraham Zlotogorski
openaire   +3 more sources

Tamoxifen and meglumine antimoniate combined therapy in cutaneous leishmaniasis patients: a randomised trial

open access: yesTropical medicine & international health, 2018
There is a clear need for new strategies of leishmaniasis treatment. This work was conducted to evaluate the efficacy of the co‐administration of tamoxifen and meglumine antimoniate (SbV) in a phase II pilot clinical trial in localised cutaneous ...
P. Machado   +9 more
semanticscholar   +1 more source

The Role of Foxes in Transmitting Zoonotic Bacteria to Humans: A Scoping Review

open access: yesZoonoses and Public Health, EarlyView.
ABSTRACT Zoonotic diseases inflict substantial burdens on human and animal populations worldwide, and many of these infections are bacterial. An Australian study investigating environmental risk factors for Buruli ulcer in humans detected the causative agent, Mycobacterium ulcerans, in the faeces of wild foxes, a novel finding that suggests foxes may ...
Emma C. Hobbs   +6 more
wiley   +1 more source

Mini-Exon Genotyping of Leishmania Species in Khuzestan Province, Southwest Iran [PDF]

open access: yesIranian Journal of Parasitology, 2010
Background: Leishmaniasis is a protozoan disease cause by Leishmania genus. Anthroponotic and zoono­tic cutaneous leishmaniasis are endemic in Iran. The aim of this study was to identify the causative agent of cutaneous leishmaniasis by mini-exon gene in
J Saki   +7 more
doaj   +1 more source

Multiple Bilateral Erythematous and Suppurative Cutaneous Nodules in a 40‐Year‐Old Indian Female

open access: yes
JEADV Clinical Practice, EarlyView.
Aditi Anand   +2 more
wiley   +1 more source

Validated LC‐MS/MS Method for Quantifying the Antiparasitic Nitroimidazole DNDI‐0690 in Preclinical Target Site PK/PD Studies

open access: yesBiomedical Chromatography, Volume 39, Issue 8, August 2025.
ABSTRACT Understanding the target site pharmacokinetics (PK) of the nitroimidazole analog DNDI‐0690, a potential drug for the neglected parasitic disease leishmaniasis, is important due to the diversity of infected tissue sites and potential drug penetration variability.
Wietse M. Schouten   +7 more
wiley   +1 more source

Efficient and Rapid Arylation of NH₂‐Unprotected Bromobisindole Ethanamines via Suzuki‐Miyaura Coupling: Generating New Leads Against Leishmania

open access: yesChemistry – A European Journal, Volume 31, Issue 43, August 1, 2025.
A library of novel bisindole derivatives was synthesized through an optimized rapid Suzuki‐Miyaura coupling reaction, utilizing NH2‐unprotected bromobisindole ethanamines and boronic acids with yields up to 93%. The compounds were screened for their activity against L. infantum promastigotes.
Alessandro Buono   +8 more
wiley   +1 more source

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