Results 41 to 50 of about 4,991 (157)

Mucocutaneous leishmaniasis in Australia: A case report

Asian Pacific Journal of Tropical Medicine
Rationale: Australia is the only inhabited continent, which is not endemic to leishmaniasis. There are some published articles reporting cutaneous leishmaniasis in travellers, immigrants and refugees.
Anjali Abraham, Mini Jacob, Connor Wright, Belle Culhane   +3 more
doaj   +1 more source

Is the Clinical Diagnosis of Cutaneous Leishmaniasis Justified in Endemic Regions?

مجله كليه طب الكندي, 2023
Leishmaniasis is a transmissible infection brought about by an obligatory intracellular protozoan from the genus Leishmania.  It occurs worldwide in tropical and subtropical regions and can be burdensome in resource-constrained countries.
Mahmood D. Al-Mendalawi
doaj   +1 more source

Novel Nonsense Mutation in SMARCD2 Gene Results in Dysplasia of All Myeloid Cell Lines

eJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Introduction Specific granule deficiency type II (SGD2) is a rare heterogeneous congenital disease characterized by early‐onset life‐threatening infections. SGD2 is caused by autosomal recessive mutations in the SMARCD2 gene. Methods Prenatal screening in our patient revealed a novel homozygous nonsense mutation in SMARCD2 (c.208C>T, p.Gln70*).
Michelle A. E. Brouwer, Arie Arensman, H. Rob Taal, Emilie P. Buddingh, Su Ming Sun, Anthon Hulsmann, Lenneke Waals‐Prinzen   +6 more
wiley   +1 more source

Clinical pattern and treatment outcome of cutaneous leishmaniasis patients in Somali region, eastern Ethiopia

Skin Health and Disease
Background Neglected tropical diseases, affecting over a billion people, include leishmaniasis, a protozoan parasite found in over 20 species. It is classified into three types: visceral, cutaneous, and muco‐cutaneous leishmaniasis, with cutaneous ...
Abdilahi Ibrahim Muse, Muse Obsiye Ibrahim, Muse Ahmed Ibrahim   +2 more
doaj   +1 more source

Mitochondrial Dysfunction Induced by a Novel Salicylate‐Based 1,2,3‐Triazole Salt With Potent Antileishmanial Activity

Chemical Biology &Drug Design, Volume 106, Issue 6, December 2025.
A novel salicylate‐based 1,2,3‐triazole salt was synthesized and demonstrated potent and selective activity against Leishmania amazonensis. The most active compound induced mitochondrial dysfunction without hemolytic effects. In silico analyses also suggested favorable pharmacokinetic properties and oral bioavailability.
Bruno A. De Oliveira, Ari Sérgio de Oliveira Lemos, João Pedro Reis Costa Bastos, Luciana Maria Ribeiro Antinarelli, Ana Luiza Ribeiro de Freitas, Raissa Guedes Mattosinhos Ribeiro, Adolfo Firmino da Silva Neto, Elaine Soares Coimbra, Adilson David Da Silva   +8 more
wiley   +1 more source

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

Tropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas, Job Alves de Souza Filho, Janete Soares Coelho Santos, Felipe Campos de Melo Iani, Cristiane Faria de Oliveira Scarponi   +4 more
wiley   +1 more source

Progress of Mucocutaneous Leishmaniasis to Drug Nonresponsive Diffuse Cutaneous Leishmaniasis in Ethiopia. A Case Report

International Medical Case Reports Journal, 2020
Banchamlak Tegegne,1 Getaneh Alemu2 1Amhara Public Health Institute, Bahir Dar, Ethiopia; 2Department of Medical Laboratory Science, Bahir Dar University, Bahir Dar, EthiopiaCorrespondence: Getaneh Alemu PO Box 79 Tel +251922842776Email getanehmlt@gmail ...
Tegegne B, Alemu G
doaj  

Leishmaniasis: Recent epidemiological studies in the Middle East

Frontiers in Microbiology, 2023
Leishmaniasis, one of the most neglected tropical diseases (NTDs), is the third most important vector-borne disease worldwide. This disease has a global impact and severity of the infection and is greatest in the Middle East.
Chinyere A. Knight, David R. Harris, Shifaa O. Alshammari, Ayele Gugssa, Todd Young, Clarence M. Lee   +5 more
doaj   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

A Forgotten Foe Returns: The Diagnostic Odyssey of Kala‐Azar Masquerading as Myelodysplastic Syndrome in a Post‐Elimination Era

Clinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty, Saiful Islam Chowdhury, Tahmidur Rahman, Tanveer Al Razi Khan, Swagota Roy, Faiza Ahmmed, Md. Sabbir Hossain, Ibrahim Khalil   +7 more
wiley   +1 more source