Results 71 to 80 of about 9,597 (197)

Diagnosis of leishmaniasis

open access: yesJournal of Infection in Developing Countries, 2014
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous,
Ehab Kotb Elmahallawy   +6 more
doaj   +1 more source

Gain-of-function STAT1 mutation and visceral leishmaniasis

open access: yesEinstein (São Paulo), 2022
Gain-of-function mutations in the STAT1 gene have been initially associated with chronic mucocutaneous candidiasis. However, further research has shown that STAT1 GOF variants may increase susceptibility to infection by other intracellular pathogens ...
Paula Teixeira Lyra   +6 more
doaj   +1 more source

Natural history of a visceral leishmaniasis outbreak in highland Ethiopia [PDF]

open access: yes, 2009
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the
Alvar, J   +14 more
core   +1 more source

Mapping the Burden of Tegumentary Leishmaniasis in South America: A Systematic Review and Meta‐Analysis

open access: yesTropical Medicine &International Health, Volume 30, Issue 12, Page 1261-1268, December 2025.
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas   +4 more
wiley   +1 more source

Cutaneous, mucocutaneous and visceral leishmaniasis in Sweden from 1996–2016: a retrospective study of clinical characteristics, treatments and outcomes

open access: yesBMC Infectious Diseases, 2018
Background Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries due to increased migration and ...
Hedvig Glans   +4 more
doaj   +1 more source

Treatment of cutaneous leishmaniasis among travellers [PDF]

open access: yes, 2017
Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over the last 10 years. Based on geographical distribution,
Beck, B.   +4 more
core  

Engineering synergistically active and bioavailable cost-effective medicines for neglected tropical diseases; the role of excipients [PDF]

open access: yes, 2017
Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world threatening 350 million people mostly in developing countries.
Dea Ayuela, Maria Auxiliadora   +2 more
core   +2 more sources

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

open access: yesVeterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis   +9 more
wiley   +1 more source

Travelers With Cutaneous Leishmaniasis Cured Without Systemic Therapy [PDF]

open access: yes, 2017
Guidelines recommend wound care and/or local therapy as first-line treatment for cutaneous leishmaniasis. An analysis of a referral treatment program in 135 travelers showed that this approach was feasible in 62% of patients, with positive outcome in 83%
Abergel, H.   +97 more
core  

A Forgotten Foe Returns: The Diagnostic Odyssey of Kala‐Azar Masquerading as Myelodysplastic Syndrome in a Post‐Elimination Era

open access: yesClinical Case Reports, Volume 13, Issue 11, November 2025.
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty   +7 more
wiley   +1 more source

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