Results 71 to 80 of about 9,597 (197)
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous,
Ehab Kotb Elmahallawy +6 more
doaj +1 more source
Gain-of-function STAT1 mutation and visceral leishmaniasis
Gain-of-function mutations in the STAT1 gene have been initially associated with chronic mucocutaneous candidiasis. However, further research has shown that STAT1 GOF variants may increase susceptibility to infection by other intracellular pathogens ...
Paula Teixeira Lyra +6 more
doaj +1 more source
Natural history of a visceral leishmaniasis outbreak in highland Ethiopia [PDF]
In May 2005, visceral leishmaniasis (VL) was recognized for the first time in Libo Kemken, Ethiopia, a highland region where only few cases had been reported before. We analyzed records of VL patients treated from May 25, 2005 to December 13, 2007 by the
Alvar, J +14 more
core +1 more source
ABSTRACT Introduction In recent years, the global burden of tegumentary leishmaniasis (TL) has significantly increased in the Americas. Objective To estimate the prevalence of TL in South America based on publications from the past 13 years. Methods Three databases were searched, and articles were selected based on inclusion criteria and methodological
Sérgio Caldas +4 more
wiley +1 more source
Background Leishmaniasis is a neglected and poorly reported parasitic infection transmitted by sand flies in tropical and subtropical regions. Knowledge about leishmaniasis has become important in non-endemic countries due to increased migration and ...
Hedvig Glans +4 more
doaj +1 more source
Treatment of cutaneous leishmaniasis among travellers [PDF]
Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over the last 10 years. Based on geographical distribution,
Beck, B. +4 more
core
Engineering synergistically active and bioavailable cost-effective medicines for neglected tropical diseases; the role of excipients [PDF]
Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world threatening 350 million people mostly in developing countries.
Dea Ayuela, Maria Auxiliadora +2 more
core +2 more sources
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis +9 more
wiley +1 more source
Travelers With Cutaneous Leishmaniasis Cured Without Systemic Therapy [PDF]
Guidelines recommend wound care and/or local therapy as first-line treatment for cutaneous leishmaniasis. An analysis of a referral treatment program in 135 travelers showed that this approach was feasible in 62% of patients, with positive outcome in 83%
Abergel, H. +97 more
core
ABSTRACT We report a diagnostically complex case of visceral leishmaniasis (Kala‐azar) in a 73‐year‐old male from a country where the disease was eliminated in 2023. The patient presented with a 2‐month history of low‐grade fever, fatigue, progressive skin hyperpigmentation over 2 years, and hepatosplenomegaly.
Sumaya Khan Mifty +7 more
wiley +1 more source

