Results 1 to 10 of about 17,469 (165)
Relationship Between Hepcidin, Iron Metabolism, Inflammation and Hypersplenism in Anaemia of Kala-Azar. [PDF]
Parasite ImmunolABSTRACT Kala‐azar, or visceral leishmaniasis (VL), is a parasitic disease caused by Leishmania spp., characterised by fever, weight loss, splenomegaly, hepatomegaly, and anaemia. This study evaluated the relationship between hepcidin, inflammation, iron metabolism, and hypersplenism in VL‐associated anaemia. In this cross‐sectional study, confirmed VL
Freitas AFA +8 more
europepmc +2 more sources
Humanised Mice in Cutaneous Leishmaniasis-T-Cell Recruitment Into Human Skin Transplants After Leishmania major Infection. [PDF]
Exp DermatolABSTRACT Treatment against leishmaniasis is associated with severe side effects, high costs, and parasitic resistance. Preclinical models such as humanised mice would aid therapeutic improvement or the development of a vaccine. We developed a model in which human skin transplants on immunodeficient mice are infected with Leishmania major.
Miao L +4 more
europepmc +2 more sources
Therapeutic Advances in Infectious Disease, 2021 Visceral leishmaniasis carries a significant burden of disease in the Americas with up to 7000 cases reported annually. There are several reports of autochthonous visceral leishmaniasis cases in the Caribbean, including the Dominican Republic, Guadalupe,
Gerardine García Oronoz +4 more
doaj +1 more source
Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection. [PDF]
PLoS Neglected Tropical Diseases, 2013 Visceral leishmaniasis is a parasitic disease associated with high mortality. The most important foci of visceral leishmaniasis in Ethiopia are in the Northwest and are predominantly associated with high rates of HIV co-infection.
Yegnasew Takele +14 more
doaj +1 more source
Clinical Case Reports, 2023 Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh +6 more
doaj +1 more source
Visceral leishmaniasis in non‐endemic rural hilly region of Nepal: A case report
Clinical Case Reports, 2022 Visceral leishmaniasis is the most severe form of leishmaniasis, caused by the obligate intracellular protozoan parasites Leishmania donovani or L. infantum, transmitted by the bite of phlebotomine sand fly.
Kapil Belbase +4 more
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Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
Journal of Tropical Medicine, 2021 Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America.
Pashupati Pokharel +2 more
doaj +1 more source
Gates Open Research, 2019 Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
doaj +1 more source
Leishmaniasis in the United States: Emerging Issues in a Region of Low Endemicity
Microorganisms, 2021 Leishmaniasis, a chronic and persistent intracellular protozoal infection caused by many different species within the genus Leishmania, is an unfamiliar disease to most North American providers.
John M. Curtin, Naomi E. Aronson
doaj +1 more source
BMC Public Health, 2017 Background There is paucity of data on quality of life as a dimension of treatment outcome among Visceral Leishmaniasis and HIV coinfected patients. This study sought to explore perceived quality of life among Visceral Leishmaniasis and HIV coinfected ...
Mekuriaw Alemayehu +3 more
doaj +1 more source