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Infectious Disease Clinics of North America, 2012 Visceral leishmaniasis (VL) is a vector-borne parasitic disease targeting tissue macrophages. It is among the most neglected infectious diseases. Classical manifestations of VL include chronic fever, hepatosplenomegaly, and pancytopenia. Most cases can be detected through serologic and molecular testing.
van Griensven, J., Diro, E.
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Therapeutic Advances in Infectious Disease, 2021 Visceral leishmaniasis carries a significant burden of disease in the Americas with up to 7000 cases reported annually. There are several reports of autochthonous visceral leishmaniasis cases in the Caribbean, including the Dominican Republic, Guadalupe,
Gerardine García Oronoz +4 more
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Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection. [PDF]
PLoS Neglected Tropical Diseases, 2013 Visceral leishmaniasis is a parasitic disease associated with high mortality. The most important foci of visceral leishmaniasis in Ethiopia are in the Northwest and are predominantly associated with high rates of HIV co-infection.
Yegnasew Takele +14 more
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Visceral leishmaniasis in non‐endemic rural hilly region of Nepal: A case report
Clinical Case Reports, 2022 Visceral leishmaniasis is the most severe form of leishmaniasis, caused by the obligate intracellular protozoan parasites Leishmania donovani or L. infantum, transmitted by the bite of phlebotomine sand fly.
Kapil Belbase +4 more
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Immunity to Visceral Leishmaniasis [PDF]
Journal of Tropical Medicine, 2012 Peer ...
Ali, Nahid Ben +3 more
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Clinical Case Reports, 2023 Key Clinical Message Visceral leishmaniasis and hemophagocytic lymphohistiocytosis share many features in common and may coincide in the same patient. Timely diagnosis and management of visceral leishmaniasis could save patients from unnecessary toxic ...
Anwar I. Joudeh +6 more
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Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review
Journal of Tropical Medicine, 2021 Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America.
Pashupati Pokharel +2 more
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Immunobiology of visceral leishmaniasis [PDF]
Frontiers in Immunology, 2012 Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania donovani and Leishmania infantum (Leishmania chagasi in the Americas). These Leishmania species infect macrophages throughout the viscera, and parasites are typically found in the spleen, liver, and bone marrow.
Kumar, Rajiv, Nylén, Susanne
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Diagnosis of visceral leishmaniasis [PDF]
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2011 Leishmaniasis is a vector-borne disease with up to 350 million people at risk of infection worldwide. Among its different clinical manifestations, visceral is the most severe form. Since clinical features of visceral leishmaniasis (VL) mimic several other common diseases, accurate diagnosis is crucial as the treatment is associated with significant ...
Pankaj, Srivastava +3 more
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Gates Open Research, 2019 Visceral leishmaniasis (VL) is a neglected tropical disease (NTD) caused by Leishmania protozoa that are transmitted by female sand flies. On the Indian subcontinent (ISC), VL is targeted by the World Health Organization (WHO) for elimination as a public
NTD Modelling Consortium Visceral Leishmaniasis Group
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