Results 111 to 120 of about 83,665 (235)

Arginase activity - a marker of disease status in patients with visceral leishmaniasis in ethiopia. [PDF]

open access: yes, 2013
The underlying mechanisms resulting in the profound immune suppression characteristic of human visceral leishmaniasis (VL) are not fully understood. Here, we tested the hypothesis that arginase, an enzyme associated with immunosuppression, is higher in ...
Corset, C   +79 more
core   +1 more source

Palpebral leishmaniasis

open access: yesClinical Case Reports
Key Clinical MessageLeishmaniasis can mimic many conditions, including hordeolum, basal cell carcinoma, and squamous cell carcinoma. The presence of kinetoplast in free‐form or intramacrophage amastigotes, ensuring us to establish the microscopic diagnosis of leishmaniasis.
Mohammad Sharifi   +3 more
openaire   +3 more sources

Synthesis and Antiparasitic Activities of New Organometallic Derivatives of the Benzimidazole Anthelmintic Drugs

open access: yesChemBioChem, Volume 27, Issue 15, 14 August 2026.
Organometallic derivatization of existing drugs is a common strategy to look for new drug candidates. This work describes the derivatization of the benzimidazole anthelmintic scaffold, from the synthesis of the organometallic derivatives to the evaluation of their biological properties. It highlights a broad range of antiparasitic activities and leaves
Corentin Ludwig   +14 more
wiley   +1 more source

HetCA/STOCSY‐Guided Dereplication of Artemisia arborescens Reveals Furofuran Lignans with Antileishmanial Effects

open access: yesChemMedChem, Volume 21, Issue 15, 14 August 2026.
Bioactive metabolites can remain hidden in negligible activity extracts. A statistical spectroscopy–driven dereplication workflow integrating the HeteroCovariance Approach (HetCA) and Statistical Total Correlation Spectroscopy (STOCSY) prioritized furofuran lignans in Artemisia arborescens, identifying three compounds with moderate antileishmanial ...
Olga Karoutzou   +6 more
wiley   +1 more source

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.

open access: yes, 2002
Visceral leishmaniasis is common in less developed countries, with an estimated 500000 new cases each year. Because of the diversity of epidemiological situations, no single diagnosis, treatment, or control will be suitable for all.
Croft, Simon L   +27 more
core   +1 more source

Of cattle, sand flies and men : a systematic review of risk factor analyses for South Asian visceral leishmaniasis and implications for elimination [PDF]

open access: yes, 2010
Background: Studies performed over the past decade have identified fairly consistent epidemiological patterns of risk factors for visceral leishmaniasis (VL) in the Indian subcontinent.
Courtenay, Orin   +8 more
core   +1 more source

Determinants of bednet ownership and use in visceral leishmaniasis-endemic areas of the Indian subcontinent.

open access: yes, 2010
OBJECTIVE: To document ownership and use of bednets with its determinants in the visceral leishmaniasis (VL)-endemic region where mainly non-insecticide impregnated nets are available through commercial channels, and bednets are being considered as a ...
Singh, SP   +19 more
core   +1 more source

The transmission dynamics of canine American cutaneous leishmaniasis in Huánuco, Peru. [PDF]

open access: yes, 2003
The epidemiology of canine American cutaneous leishmaniasis (ACL) due to Leishmania (Viannia) spp. was investigated in Huánuco, Peru to 1) describe the natural course of canine L.
Reithinger, Richard   +2 more
core   +1 more source

Causes of Pediatric Visceral Leishmaniasis in Southeastern Iran

open access: yesIranian Journal of Parasitology, 2014
Leishmania infantum is the most frequent cause of visceral leishmaniasis and L. tropica has been rarely linked to the disease in Iran. In this study, bone marrow aspirates were collected from 10 child patients, suspected with visceral leishmaniasis ...
Ali Hosseininasab   +4 more
doaj  

Leptin enhances the efficacy of glucantime to modulate macrophage polarization toward the M1 phenotype in Leishmania tropica-infected macrophages

open access: yesParasites & Vectors
Background Macrophages are essential immune cells during Leishmania infection, as their polarization toward M1/M2 phenotypes determines disease outcome.
Alireza Keyhani   +3 more
doaj   +1 more source

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