Results 91 to 100 of about 109,328 (235)

A Papillary Thyroid Cancer Metastasis Presented as a Ciliated Cyst in the Neck: An Unusual Presentation

open access: yesClinical Case Reports
This case highlights the diagnostic challenges of neck masses that appear benign but are malignant upon histological examination. It underscores the need for comprehensive diagnostic procedures to rule out cancer.
Ali Asilian   +2 more
doaj   +1 more source

Leishmaniasis.

open access: yesRevista de la Facultad de Medicina, Universidad Nacional de Colombia, 1948
Historia de la ulcera leishmaniásica en Colombia, y tratamiento de la Leishmaniasis por medio del difosfato de cloro ...
openaire   +2 more sources

Palpebral leishmaniasis

open access: yesClinical Case Reports
Key Clinical MessageLeishmaniasis can mimic many conditions, including hordeolum, basal cell carcinoma, and squamous cell carcinoma. The presence of kinetoplast in free‐form or intramacrophage amastigotes, ensuring us to establish the microscopic diagnosis of leishmaniasis.
Mohammad Sharifi   +3 more
openaire   +3 more sources

Targeting Kinetoplastid Parasites with ProTide Prodrugs: A Proof‐of‐Concept Study

open access: yesChemMedChem, Volume 21, Issue 7, 14 April 2026.
Neglected tropical diseases (NTDs) remain a major global health challenge, particularly in low‐ and middle‐income countries. Kinetoplastid parasites causing Chagas disease, leishmaniasis, and African trypanosomiasis rely on host purine salvage pathways, making nucleoside analogues attractive therapeutic candidates.
Silvester Lowe   +6 more
wiley   +1 more source

Causes of Pediatric Visceral Leishmaniasis in Southeastern Iran

open access: yesIranian Journal of Parasitology, 2014
Leishmania infantum is the most frequent cause of visceral leishmaniasis and L. tropica has been rarely linked to the disease in Iran. In this study, bone marrow aspirates were collected from 10 child patients, suspected with visceral leishmaniasis ...
Ali Hosseininasab   +4 more
doaj  

Leptin enhances the efficacy of glucantime to modulate macrophage polarization toward the M1 phenotype in Leishmania tropica-infected macrophages

open access: yesParasites & Vectors
Background Macrophages are essential immune cells during Leishmania infection, as their polarization toward M1/M2 phenotypes determines disease outcome.
Alireza Keyhani   +3 more
doaj   +1 more source

Utility of Lymph Node Aspiration in the Diagnosis of Visceral Leishmaniasis in Sudan. [PDF]

open access: yes, 2007
We evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) using a diagnostic titer > or = 1:6,400 in 7,880 suspected VL patients ...
Babiker, Z O E   +4 more
core   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon   +12 more
wiley   +1 more source

Linking Targeted Pancreatic Cancer Genes With Metabolic Disorders: A Cross‐Species Translational Pathway

open access: yesCancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Introduction Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies because of its typically late diagnosis and limited treatment options, with surgical resection being the primary intervention. Emerging studies have consistently reported associations between PDAC and metabolic dysfunctions, including obesity ...
Dipanwita Nath   +5 more
wiley   +1 more source

Detection and identification of Leishmania species within naturally infected sand flies in the Andean areas of Ecuador by a polymerase chain reaction [PDF]

open access: yes, 2005
The surveillance of prevalent Leishmania and sand fly species in endemic areas is important for prediction of the risk and expansion of leishmaniasis. In this study, we developed a polymerase chain reaction (PCR)-based method for detection of Leishmania ...
Barroso, Paola Andrea   +11 more
core   +1 more source

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