Results 81 to 90 of about 83,665 (235)
Background: Cutaneous leishmaniasis (CL) is associated with a broad and complex clinical spectrum of diseases. The objectives of this study were to assess the clinical features and identification of the causative agents of CL in a well-known focus of ...
Ahmad KHOSRAVI +7 more
doaj
Summary Precursor‐targeted immune‐mediated anaemia (PIMA) is an increasingly recognised cause of nonregenerative anaemia in dogs and may be difficult to distinguish from infectious or other immune‐mediated conditions. This report describes a dog presenting severe nonregenerative anaemia, leukopenia and thrombocytopenia, initially testing seroreactive ...
Vinícius dos Santos Resende Rodrigues +5 more
wiley +1 more source
The use of K39 test in the diagnosis of visceral leishmaniasis [PDF]
From time to time patients admitted with fever of unknown origin prove to be a diagnostic dilemma. While textbooks describe typical symptoms and signs, and also diagnostic tests, these are not always helpful.
Sciberras, Robert
core
Background. A consistent treatment has not been proposed for treatment of Striae Alba (SA). The present study was designed to compare the fractionated microneedle radiofrequency (FMR) alone and in combination with fractional carbon dioxide laser (FMR ...
Farahnaz Fatemi Naeini +4 more
doaj +1 more source
Structural Insights Into the Function of Leishmania major Adenylosuccinate Lyase
ABSTRACT One of several intriguing aspects of kinetoplastid biochemistry is the complete dependence on host purines and purine recycling due to the lack of a de novo purine biosynthesis pathway. Adenylosuccinate lyase (ASL, EC 4.3.2.2) is a key enzyme in the purine synthesis pathway responsible for the conversion of adenylosuccinate into adenosine ...
Ivan R. e Silva +10 more
wiley +1 more source
Clinical features and diagnosis of 42 travellers with cutaneous leishmaniasis.
BACKGROUND: Leishmania species that occur within different geographical areas may cause different clinical manifestations, virulence and drug sensitivity. Patients/Methods.
Lockwood, D +7 more
core +1 more source
Integrated mapping of establishment risk for emerging vector-borne infections: a case study of canine leishmaniasis in southwest France. [PDF]
BACKGROUND: Zoonotic visceral leishmaniasis is endemic in the Mediterranean Basin, where the dog is the main reservoir host. The disease's causative agent, Leishmania infantum, is transmitted by blood-feeding female sandflies.
Hartemink, Nienke +40 more
core +3 more sources
Evaluation of two libraries of peptoid‐based compounds for inhibitory activity against PfA‐M1 from Plasmodium falciparum, TcLAP from Trypanosoma cruzi, and LmLAP from Leishmania major reveals the crucial role of hydrophobic interactions in the inhibition process of these parasite metallo‐aminopeptidases.
Mirta Elisa Aguado +16 more
wiley +1 more source
The history of leishmaniasis [PDF]
In this review article the history of leishmaniasis is discussed regarding the origin of the genus Leishmania in the Mesozoic era and its subsequent geographical distribution, initial evidence of the disease in ancient times, first accounts of the infection in the Middle Ages, and the discovery of Leishmania parasites as causative agents of ...
openaire +4 more sources
‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK
Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson +2 more
wiley +1 more source

