Results 141 to 150 of about 171,841 (309)
Low castes have poor access to visceral leishmaniasis treatment in Bihar, India [PDF]
Objectives Bihar, the poorest state in India, concentrates most of the visceral leishmaniasis (VL) cases in the country. A large proportion of the poor rural communities where VL is endemic are marginalized by their socio-economic status, intrinsically ...
Alvar+22 more
core +2 more sources
ABSTRACT Treatment against leishmaniasis is associated with severe side effects, high costs, and parasitic resistance. Preclinical models such as humanised mice would aid therapeutic improvement or the development of a vaccine. We developed a model in which human skin transplants on immunodeficient mice are infected with Leishmania major.
Ling Miao+4 more
wiley +1 more source
Cyclin-dependent kinase 12, a novel drug target for visceral leishmaniasis
Visceral leishmaniasis causes considerable mortality and morbidity in many parts of the world. There is an urgent need for the development of new, effective treatments for this disease.
S. Wyllie+31 more
semanticscholar +1 more source
Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. [PDF]
We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice.
Coffman, RL+4 more
core
Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism. [PDF]
BALB/c mice infected with Leishmania major develop fatal, progressive disease, despite an immune response characterized by expansion of CD4+ T cells in the draining lymph nodes.
Dawkins, RS+5 more
core +1 more source
Infantile Visceral Leishmaniasis in the Maltese Islands [PDF]
T. J. Agius-Ferrante
openalex +1 more source
Prevalence of Proteinuria in Dogs With Immune‐Mediated Disease
ABSTRACT Background Proteinuria is associated with autoimmune diseases in humans. There is minimal evidence in the veterinary literature on proteinuria and its association with immune‐mediated disease in dogs. Hypothesis Renal proteinuria is common in dogs with immune‐mediated disease. Dogs presenting with pyrexia or immune‐mediated polyarthritis (IMPA)
James C. Barton+2 more
wiley +1 more source
Review of Leishmaniasis in the Middle East and North Africa
Background Cutaneous and visceral forms of leishmaniasis are the most important protozoan infection in the Middle East and North Africa (MENA). Objectives Review the current knowledge on leishmaniasis in the MENA.
A. Tabbabi
semanticscholar +1 more source