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Current and emerging medications for the treatment of leishmaniasis
Expert Opinion on Pharmacotherapy, 2019Introduction: Leishmaniasis is a vector-borne neglected tropical disease which manifests as visceral leishmaniasis (VL), cutaneous leishmaniasis (CL), and mucocutaneous leishmaniasis (MCL).
J. Chakravarty, S. Sundar
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Acta Tropica, 2002
Leishmaniases are widespread in most countries in the Mediterranean basin, including Turkey. Two forms are observed in Turkey; Leishmania infantum is responsible from visceral leishmaniasis (VL), and L. tropica causes cutaneous leishmaniasis (CL). Phlebotomus sergenti, P. papatasi, P. major and P. syriacus are considered to be the probable vectors, and
Balcioglu, IC+4 more
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Leishmaniases are widespread in most countries in the Mediterranean basin, including Turkey. Two forms are observed in Turkey; Leishmania infantum is responsible from visceral leishmaniasis (VL), and L. tropica causes cutaneous leishmaniasis (CL). Phlebotomus sergenti, P. papatasi, P. major and P. syriacus are considered to be the probable vectors, and
Balcioglu, IC+4 more
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Journal of Infection, 2014
Leishmaniasis remains an important neglected tropical infection that affects children more than adults. Geographical variation exists in the distribution of the various Leishmania species. Although the majority of the disease burden is found in poor countries, leishmaniasis is also endemic in several countries within Southern Europe.
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Leishmaniasis remains an important neglected tropical infection that affects children more than adults. Geographical variation exists in the distribution of the various Leishmania species. Although the majority of the disease burden is found in poor countries, leishmaniasis is also endemic in several countries within Southern Europe.
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Trends in Parasitology, 2006
Leishmaniasis, a neglected tropical disease, has strong but complex links with poverty. The burden of leishmaniasis falls disproportionately on the poorest segments of the global population. Within endemic areas, increased infection risk is mediated through poor housing conditions and environmental sanitation, lack of personal protective measures and ...
Jorge Alvar, Caryn Bern, Sergio Yactayo
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Leishmaniasis, a neglected tropical disease, has strong but complex links with poverty. The burden of leishmaniasis falls disproportionately on the poorest segments of the global population. Within endemic areas, increased infection risk is mediated through poor housing conditions and environmental sanitation, lack of personal protective measures and ...
Jorge Alvar, Caryn Bern, Sergio Yactayo
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Current Opinion in Immunology, 1992
Resolution of leishmanial infections requires the expansion of specific type 1 T helper cells that secrete or express on their membrane lymphokines capable of activating macrophages that contain these parasites to a microbicidal state. Specific CD8+ T cells, which are triggered during infection, also appear to play a role in protective immunity ...
Jacques A. Louis+2 more
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Resolution of leishmanial infections requires the expansion of specific type 1 T helper cells that secrete or express on their membrane lymphokines capable of activating macrophages that contain these parasites to a microbicidal state. Specific CD8+ T cells, which are triggered during infection, also appear to play a role in protective immunity ...
Jacques A. Louis+2 more
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Leishmaniasis: where are we and where are we heading?
Parasitology Research, 2021S. Sasidharan, Prakash Saudagar
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The Immunobiology of Leishmaniasis
Clinical Infectious Diseases, 1983Members of the genus Leishmania are important intracellular pathogens that produce either cutaneous, mucocutaneous, or visceral disease in many areas of the world. In humans as well as in other mammals, the parasite is inoculated through the skin as a flagellated, extracellular promastigote by its arthropod vector, the sandfly.
Richard D. Pearson+3 more
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Recent advances and new strategies on leishmaniasis treatment
Applied Microbiology and Biotechnology, 2020B. Roatt+5 more
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Leishmaniasis: current situation and new perspectives.
Comparative Immunology, Microbiology & Infectious Diseases, 2004P. Desjeux
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