Results 51 to 60 of about 83,665 (235)

A policy for leishmaniasis with respect to the prevention and control of drug resistance. [PDF]

open access: yes, 2001
At the moment no country has a policy designed to control or prevent drug resistance in leishmaniasis. The risk of resistance is high in areas of anthroponotic visceral leishmaniasis, for example North Bihar, India, where the rate in some areas is 60 ...
Bryceson, A
core   +1 more source

Leishmania: Responding to environmental signals and challenges without regulated transcription

open access: yesComputational and Structural Biotechnology Journal, 2020
Here we describe the non-canonical control of gene expression in Leishmania, a single-cell parasite that is responsible for one of the major neglected tropical diseases.
Janne Grünebast, Joachim Clos
doaj   +1 more source

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

open access: yesJournal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang   +3 more
wiley   +1 more source

Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial [PDF]

open access: yes, 2012
Alternative treatments for visceral leishmaniasis (VL) are required in East Africa.
Makonnen, Eyasu   +151 more
core   +1 more source

Leishmania RNA Virus and Its Impact on Drug Response and Clinical Outcomes in Leishmaniasis: A Comprehensive Review

open access: yesJournal of Parasitology Research
Leishmania RNA viruses (LRVs) have emerged as significant modulators of disease severity, therapeutic response, and clinical outcomes in various forms of leishmaniasis.
Azadeh Zolfaghari   +4 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Predicting geographic variation in cutaneous leishmaniasis, Colombia. [PDF]

open access: yes, 2004
Approximately 6,000 cases of cutaneous leishmaniasis are reported annually in Colombia, a greater than twofold increase since the 1980s. Such reports certainly underestimate true incidence, and their geographic distribution is likely biased by local ...
King, Raymond J   +5 more
core   +1 more source

Synthesis, characterization, and comparative evaluation of hydroxychloroquine and its niosomal nanoformulation: anti-leishmanial, cytotoxicity, and immunomodulatory effects in photodynamic therapy

open access: yesScientific Reports
Leishmaniasis, caused by the Leishmania parasites, is a significant global health issue with treatment challenges, particularly in endemic regions such as Iran.
Elaheh Molaakbari   +7 more
doaj   +1 more source

Artificial Intelligence in Dermatology: Current Applications and Future Directions

open access: yesJEADV Clinical Practice, EarlyView.
This scoping review of 56 studies maps AI applications in dermatology. Image‐based classification for skin cancer detection dominates (48%), followed by clinical decision support (21%), teledermatology triage (11%), and predictive analytics (11%). While deep learning algorithms demonstrate diagnostic performance comparable to clinicians in controlled ...
Sofía Pérez‐Lalinde   +1 more
wiley   +1 more source

Age-related alteration of arginase activity impacts on severity of leishmaniasis. [PDF]

open access: yes, 2008
BACKGROUND: The leishmaniases are a group of vector-borne parasitic diseases that represent a major international public health problem; they belong to the most neglected tropical diseases and have one of the highest rates of morbidity and mortality. The
Asrat Hailu   +40 more
core   +2 more sources

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