Introduction In canine visceral leishmaniasis (CVL), lymphopenia, and the disorganization of lymphoid organs such as spleen and lymph nodes have been demonstrated. However, the involvement of thymus in CVL has not been evaluated so far.
Aurea V. A. daSilva +9 more
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Whole-Genome Sequencing and Comparative Genomic Analysis of Leishmania (Viannia) naiffi and L. (Viannia) shawi Reveal Species-Specific Genes and Novel Potential Drug Targets [PDF]
This study presents the complete sequencing and comparative genomic analysis of Leimania (Viannia) naiffi and Leishmania (Viannia) shawi, species of epidemiological relevance in the Brazilian Amazon.
Fabiano Reis da Silva +4 more
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Resequencing and De Novo Assembly of Leishmania (Viannia) guyanensis from Amazon Region: Genome Assessment, Phylogenetic Insights and Therapeutic Targets [PDF]
Leishmania guyanensis is one of 15 American human-pathogenic species, frequently linked to therapeutic failure due to its marked genetic plasticity and adaptability under drug pressure. To broaden the genomic understanding of this species, its biological
Lucas George Assunção Costa +6 more
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Evaluation of the Loop-Mediated Isothermal Amplification (LAMP) Technique in Swab Samples from Ulcerated Cutaneous Lesions Compared with Conventional Diagnostic Methods for American Tegumentary Leishmaniasis in Patients Treated at a Reference Center in Rio de Janeiro, Brazil [PDF]
Cutaneous leishmaniasis (CL) is a vector-borne disease caused by Leishmania spp. Molecular methods such as conventional PCR (cPCR) and real-time PCR (qPCR) show high accuracy but remain restricted to reference centers.
Elizabeth Cristina Araújo Ferreira Faulhaber +12 more
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O USO CLÍNICO DAS PENTAMIDINAS COM ESPECIAL REFERÊNCIA NAS LEISHMANIOSES [PDF]
O autor apresenta uma ampla revisão da literatura sobre as diamidinas aromáticas (Pentamidinas), dando ênfase à terapêutica das leishmanioses, considerando a possibilidade desta droga ser usada como segunda opção no tratamento das mesmas.
Jackson Maurício L. COSTA
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Susceptibility of Lutzomyia longipalpis (Lutz & Neiva, 1912) to Fludora FusionPM, a combination of clothianidin and deltamethrin: field and laboratory bioassays [PDF]
Background Insecticides remain a cornerstone in the control of vector-borne diseases. In Brazil, Alfatek 200SC—a pyrethroid (alphacypermethrin)—is recommended for controlling phlebotomine sand flies, the vectors of leishmaniases.
Greicielly Barbosa Santos Silva +9 more
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Low Plasma Lipids Are Associated with Relapsing and Lethal Visceral Leishmaniasis in HIV-Infected Patients [PDF]
Visceral leishmaniasis (VL) results from protozoa Leishmania infantum and L. donovani infection. This study investigated whether host factors would explain the relapses. First, susceptibility to amphotericin B of L.
Renata V. S. Silva +9 more
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Revisiting Leishmania (Viannia) lainsoni Silveira, Shaw, Braga, and Ishikawa, 1987: current knowledge and emerging perspectives [PDF]
More than three decades after its description, Leishmania (Viannia) lainsoni Silveira, Shaw, Braga, and Ishikawa, 1987 remains the least explored species of the subgenus Viannia Lainson and Shaw, 1987 within the genus Leishmania Ross, 1903. Although long
Thais Gouvea de Morais +3 more
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As leishmanioses têm alta prevalência no Brasil e, particularmente, em Divinópolis, Minas Gerais. O desconhecimento das enfermidades favorece sua disseminação.
Viviane Helena de França +2 more
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Saúde, ciência e desenvolvimento: a emergência da leishmaniose tegumentar americana como desafio médico-sanitário no Amazonas [PDF]
Resumo O artigo faz análise histórica da emergência da leishmaniose tegumentar americana como objeto do conhecimento e desafio médico-sanitário no Amazonas desde a década de 1970.
Cláudio de Oliveira Peixoto
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