Results 41 to 50 of about 4,280,197 (258)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Growth of the Anchovy Anchoa tricolor in a brazilian subtropical estuary
Anais da Academia Brasileira de Ciências, 2018 This study aimed to describe the growth parameters of Anchoa tricolor in a subtropical estuary. From August 2010 to July 2011, 10.009 specimens of the anchovy Anchoa tricolor, mean total length 4.2 cm (±1.45), were captured in the intertidal region of ...
BARBARA M. DE CARVALHO +2 more
doaj +1 more source
Turkish Journal of Bioscience and Collections, 2021 Objective: In this study, some growth characteristics of Barbus cyclolepis Heckel, 1837 and Gobio bulgaricus Drensky, 1926 species living in Karasu Stream, were investigated. Materials and Methods: Sampling was carried out seasonal (August 2017, November
Çiğdem Çelik, Müfit Özuluğ
doaj +1 more source
Are there sex differences in the body size of the Eurasian red squirrel in Slovakia? [PDF]
, 2015 Sexual dimorphism of the Eurasian red squirrel on five somatic variables (head-and-body length, tail length, hind foot length, ear length and body weight) was evaluated on 55 squirrels.
Krišovský, Peter +2 more
core +2 more sources
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Rat superficial masseter operates at long lengths during biting
Scientific ReportsThe operating length ranges of mammalian jaw muscles have been estimated using twitch contractions or force measurements at the bite point, prompting a consensus that jaw muscles operate at short lengths on their force-length (FL) curve.
Nicolai Konow +6 more
doaj +1 more source
Length-weight relationships of marine fishes from the central Brazilian coast [PDF]
, 2004 Parameters of the length-weight relationship are presented for 85 fish species from the marine and estuarine regions of the central Brazilian coast (latitude 13° to 23° S). Three different methods were used. A non-linear iterative process using the quasi-
Braga, A.C., Costa, P.A.S., Frota, L.O.
core
Information content versus word length in random typing [PDF]
, 2011 Recently, it has been claimed that a linear relationship between a measure of information content and word length is expected from word length optimization and it has been shown that this linearity is supported by a strong correlation between information
Ferrer-i-Cancho, Ramon +1 more
core +5 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source