Results 41 to 50 of about 4,300,134 (258)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Growth of the Anchovy Anchoa tricolor in a brazilian subtropical estuary
Anais da Academia Brasileira de Ciências, 2018 This study aimed to describe the growth parameters of Anchoa tricolor in a subtropical estuary. From August 2010 to July 2011, 10.009 specimens of the anchovy Anchoa tricolor, mean total length 4.2 cm (±1.45), were captured in the intertidal region of ...
BARBARA M. DE CARVALHO +2 more
doaj +1 more source
Turkish Journal of Bioscience and Collections, 2021 Objective: In this study, some growth characteristics of Barbus cyclolepis Heckel, 1837 and Gobio bulgaricus Drensky, 1926 species living in Karasu Stream, were investigated. Materials and Methods: Sampling was carried out seasonal (August 2017, November
Çiğdem Çelik, Müfit Özuluğ
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Rat superficial masseter operates at long lengths during biting
Scientific ReportsThe operating length ranges of mammalian jaw muscles have been estimated using twitch contractions or force measurements at the bite point, prompting a consensus that jaw muscles operate at short lengths on their force-length (FL) curve.
Nicolai Konow +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The relationship of protein conservation and sequence length
BMC Evolutionary Biology, 2002 Background In general, the length of a protein sequence is determined by its function and the wide variance in the lengths of an organism's proteins reflects the diversity of specific functional roles for these proteins.
Panchenko Anna R +4 more
doaj +1 more source
The Bond-Energy Bond-Order (BEBO) Model of Chemisorption [PDF]
, 1973 The bond-energy bond-order (BEBO) model of chemisorption allows an estimate to be made of the interaction energy between a gaseous specie and a solid surface as a function of either bond length or bond order, i.e., the length or order of either the gas ...
Weinberg, W. H.
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source