Results 51 to 60 of about 3,146 (154)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Length-Weight relationship of 13 fish species from the Lower Sakarya River, Turkey

Aquatic Sciences and Engineering, 2019
In this study, a total of 1935 fish samples were collected monthly between June 2017 and May 2018 belonging to 5 families; Cyprinidae, Siluridae, Percidae, Centrarchidae and Esocidae from the lower Sakarya River, Turkish shores of the western Black Sea ...
İsmail Reis, Hasan Cerim, Celal Ateş
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Comparative analysis of carapace length-weight relationship and condition factor of Panulirus stimpsoni and Panulirus japonicus, along Jeju Island, South Korea

Fisheries and Aquatic Sciences
The economic significance of spiny lobsters, Panulirus japonicus and Panulirus stimpsoni, is substantial in South Korea. However, their biological characteristics are not well documented.
Jun-Hwan Byun, Ji-Yeon Hyeon, Weerasinghe Pathiranage Jonathan, Han-Jun Kim, Yeong-Hyun Cho, Young-Seock Yoon, Sachithra Amarin Hettiarachchi, Sung-Pyo Hur   +7 more
doaj   +1 more source

Prevalence and Intensity of Ectoparasites on Clarias gariepinus From Aquaculture Pond in Aceh Besar District, Indonesia

Jurnal Biodjati, 2019
Information related to the prevalence and intensity of para-sites in an aquatic environment is crucial as preventive and responsive efforts to manage aquatic resources, especially for fish farming pur-poses.
Fitria Nelda Fautama, Ilham Zulfahmi, Muliari Muliari, Adian Aristia Anas   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Length–Weight Relationships for Freshwater Fish Species in Küçük Menderes River Basin, Turkey

Frontiers in Marine Science, 2015
This study provides length–weight relationships for ten fish species from Küçük Menderes River Basin, inland water systems of Western Anatolian Region, Turkey.
Mustafa Korkmaz, Mustafa Korkmaz
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source