Results 61 to 70 of about 318,037 (203)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Length–length and length-weight relationships and condition factor of nine freshwater fish species of Nageshwari, Bangladesh

International Journal of Aquatic Biology, 2015
The research carried out the length-length relationships (LLR), length-weight relationship (LWR) and condition factor of nine freshwater small indigenous species viz. G. giuris, E. Danricus, M. pancalus, L. guntea, C. fasciatus, P. sophore, H.  Fossilis,
Most Habiba Ferdaushy, Mohammad Manjurul Alam   +1 more
doaj  

Length–Weight Relationships of the Prized Sea Cucumber Holothuria lessoni from In Situ and Ex Situ Measurements

Journal of Marine Science and Engineering
Fisheries science draws on morphometric data for stock assessments. Length–weight relationships are essential for estimating body weight from length measurements taken either underwater (in situ) or out of the water (ex situ).
Lea A. F. Djenidi, Steven W. Purcell, Aaron W. Thornton, Hugues Gossuin, Antoine Gilbert   +4 more
doaj   +1 more source

Length-weight and length-length relationships of seven loach species (Teleostei: Cypriniformes) from five localities in northern Western Ghats, India

Journal of Threatened Taxa, 2015
Length-weight (LWR) and length-length (LLR) relationships of seven loach species (Teleostei: Cypriniformes): Botia striata, Lepidocephalichthys thermalis, Paracanthocobitis mooreh, Indoreonectes evezardi, Nemacheilus anguilla, Nemachilichthys rueppelli ...
Ashwini Keskar, Pradeep Kumkar, Mandar S. Paingankar, Anand Padhye, Neelesh Dahanukar   +4 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Length-weight relationships of six freshwater fish species from Lake Kirkkojärvi, Finland

Croatian Journal of Fisheries, 2017
Length-weight relationships (LWRs) and length-length relationships (LLRs) were determined for six fish species: Alburnus alburnus, Blicca bjoerkna, Gymnocephalus cernua, Perca fluviatilis, Rutilus rutilus and Sander lucioperca caught using a Nordic multi-
Gama José, Nyberg Maria
doaj   +1 more source