Results 91 to 100 of about 1,945,113 (313)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Length-weight relationship of intertidal molluscs from Mumbai, India [PDF]

open access: yes, 2002
A study on the length-weight relationship of common intertidal molluscs from Mumbai showed a high degree of correlation between their length and weight.
Jaiswar, A.K., Kulkarni, B.G.
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

The age and growth of the tongue sole Cynoglossus canariensis (Steind 1882) [PDF]

open access: yes, 1983
The geometric mean regression equation for the weight; length relationship of Cynoglossus canariensis was W = 0.0025 L super(3.1770). The Von Bertalanffy constants Woo, Loo, K, and to were 507.5852 g, 47.3683 cm, 0.3333 and 0.1397 for males and 839.0753 ...
Ajayi, T.O.
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Length-weight relationship Megalaspis cordyla (Linnaeus, 1758) along north west coast of India [PDF]

open access: yes, 1991
Total length and total weight relationship of Megalaspis cordyla (Linnaeus, 1758) a carangid fish, along north west coast of India has been worked out.
Acharya, P., Jaiswar, A.K.
core  

Length weight relationships of Nigerian freshwater fishes [PDF]

open access: yesNaga, 1996
Length-weight relationships of 73 fish populations, covering 20 families, 28 genera and 40 species inhabiting freshwater ecosystems in Nigeria, were estimated (73 cases) or assembled from the literature (20 cases), and tested for difference between ecosystem types, There were no significant differences in the exponent of these relationships between ...
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Comparative analysis of carapace length-weight relationship and condition factor of Panulirus stimpsoni and Panulirus japonicus, along Jeju Island, South Korea

open access: yesFisheries and Aquatic Sciences
The economic significance of spiny lobsters, Panulirus japonicus and Panulirus stimpsoni, is substantial in South Korea. However, their biological characteristics are not well documented.
Jun-Hwan Byun   +7 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

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