Results 61 to 70 of about 508,457 (266)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Length-weight relationships of Lake Kariba fishes [PDF]

open access: yesNaga, 1992
The parameters a and b of the length-weight relationship of the form W = aL super(b) were computed for 40 species from tables/graphs presented in E. Balon's Fishes of Lake Kariba, Africa.
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Length-Weight relationship of 13 fish species from the Lower Sakarya River, Turkey

open access: yesAquatic Sciences and Engineering, 2019
In this study, a total of 1935 fish samples were collected monthly between June 2017 and May 2018 belonging to 5 families; Cyprinidae, Siluridae, Percidae, Centrarchidae and Esocidae from the lower Sakarya River, Turkish shores of the western Black Sea ...
İsmail Reis, Hasan Cerim, Celal Ateş
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Comparative analysis of carapace length-weight relationship and condition factor of Panulirus stimpsoni and Panulirus japonicus, along Jeju Island, South Korea

open access: yesFisheries and Aquatic Sciences
The economic significance of spiny lobsters, Panulirus japonicus and Panulirus stimpsoni, is substantial in South Korea. However, their biological characteristics are not well documented.
Jun-Hwan Byun   +7 more
doaj   +1 more source

Prevalence and Intensity of Ectoparasites on Clarias gariepinus From Aquaculture Pond in Aceh Besar District, Indonesia

open access: yesJurnal Biodjati, 2019
Information related to the prevalence and intensity of para-sites in an aquatic environment is crucial as preventive and responsive efforts to manage aquatic resources, especially for fish farming pur-poses.
Fitria Nelda Fautama   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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