Results 71 to 80 of about 421,254 (307)

New-Onset Depression Following Hip Fracture Is Associated With Increased Length of Stay in Hospital and Rehabilitation Centers [PDF]

open access: yes, 2014
This article examines the coincident effects of new-onset depression post hip fracture on length of hospital stay, readmission rates, and incidence of infections in older adults.
Janet M. Lord   +12 more
core   +1 more source

A Survey of Patients\' Length of Stay and Its Effective Predictors in Emergency Departments of TUMS Selected Hospitals

open access: yesپیاورد سلامت, 2017
Background and Aim: Hospitals should be able to satisfy their clients’ needs in less time and with best quality possible. Length of Stay (LOS) in hospitals is considered as a key performance indicator, especially in emergency departments.
Hamed Basir Ghafouri   +4 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Factors associated with prolonged hospitalization of patients with corona virus disease (COVID-19) in Uganda: a retrospective cohort study

open access: yesTropical Medicine and Health, 2022
Introduction Identification of factors predicting prolonged hospitalization of patients with coronavirus disease (COVID-19) guides the planning, care and flow of patients in the COVID-19 Treatment Units (CTUs).
Prossie M. Ingabire   +14 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Inpatient psychiatric length of stay and readmission rates [PDF]

open access: yes, 2007
Includes bibliographical ...
Drager, Katrina A.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Pelvic fracture does not increase mortality in adult trauma patients: A propensity score analysis

open access: yesFormosan Journal of Surgery, 2017
Background: This study was designed to investigate the impact of pelvic fracture on the outcome of trauma patients. Methods: Detailed data of 512 and 20,159 adult patients with and without pelvic fracture, respectively, hospitalized between January 1 ...
Ching-Hua Hsieh   +3 more
doaj   +1 more source

Psychiatric consultations and length of hospital stay

open access: yesNeurosciences, 2008
OBJECTIVE: To examine factors affecting the length of hospital stay (LOS) of patients referred to psychiatric consultation liaison (C-L) services. METHODS: The study sample prospectively included all the referrals in 2004 to the C-L psychiatry unit at King Khaled University Hospital in Riyadh, Kingdom of Saudi Arabia.
openaire   +2 more sources

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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