Results 81 to 90 of about 421,254 (307)

Reducing the length of postnatal hospital stay: implications for cost and quality of care [PDF]

, 2016
Background  UK health services are under pressure to make cost savings while maintaining quality of care. Typically reducing the length of time patients stay in hospital and increasing bed occupancy are advocated to achieve service efficiency ...
Helen Cheyne, Bowers, John, Cheyne, Helen, John Bowers   +3 more
core   +1 more source

Outcome of adult congenital heart disease patients undergoing cardiac surgery: clinical experience of dr. Sardjito hospital

BMC Proceedings, 2019
Background Patients with congenital heart disease require surgery to correct the cardiac defect they had in order to prevent heart failure. Unfortunately, data regarding outcome of adult CHD in Indonesia is still limited.
Juni Kurniawaty, Yunita Widyastuti
doaj   +1 more source

Factors influencing hospital high length of stay outliers

BMC Health Services Research, 2012
Background The study of length of stay (LOS) outliers is important for the management and financing of hospitals. Our aim was to study variables associated with high LOS outliers and their evolution over time. Methods We used hospital administrative data
Freitas Alberto, Silva-Costa Tiago, Lopes Fernando, Garcia-Lema Isabel, Teixeira-Pinto Armando, Brazdil Pavel, Costa-Pereira Altamiro   +6 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Predicting length of stay in a male medium secure psychiatric hospital [PDF]

, 2012
This thesis examines factors associated with length of hospital stay for mentally disordered offenders, detained within the medium secure psychiatric estate.
Wilkes, Victoria Louise
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Clustering patient length of stay using mixtures of Gaussian models and phase type distributions [PDF]

, 2009
Gaussian mixture distributions and Coxian phase type distributions have been popular choices model based clustering of patients' length of stay data.
Millard, P.H., McClean, S.I., El-Darzi, E., Garg, L., Meenan, B.   +4 more
core   +1 more source

Perioperative serum lactate as a predictor of post-operative length of hospital stay and in-hospital mortality in patients undergoing major emergency abdominal surgeries

Asian Journal of Medical Sciences
Background: Major surgeries can develop metabolic acidosis during the perioperative period. Any clinical condition leading to decreased tissue oxygenation causes lactate levels to rise proportionally.
Safura Riaz , Abdul Waheed Mir , Suhail Sidiq , Showkat Ahmed Gurcoo , Mohammad Akbar Shah , Falak Ara , Akif Mutahar Shah , Altaf Hussain Mir   +7 more
doaj   +1 more source

Modelling length of hospital stay in motor victims

Salud Pública de México, 2015
Objective. To analyze which socio-demographic and other factors related to motor injuries affect the length of hospital recovery stay. Materials and methods. In the study a sample of 17 932 motor accidents was used.
Mercedes Ayuso-Gutiérrez, Lluís Bermúdez-Morata, Miguel Santolino-Prieto   +2 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source