Results 111 to 120 of about 539,038 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Association Between the Emergency Department Length of Stay and in-Hospital Mortality: A Retrospective Cohort Study

, 2023
Hadiki Habib,1– 3,* Mondastri Korib Sudaryo4,* 1Doctoral Program of Epidemiology, Epidemiology Department, Faculty of Public Health, Universitas Indonesia, Depok, Indonesia; 2Emergency Unit, Dr.
Habib H, Sudaryo MK
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Time Series Analysis of Emergency Department Length of Stay per 8-Hour Shift

Western Journal of Emergency Medicine, 2012
Introduction: The mean emergency department (ED) length of stay (LOS) is considered a measure ofcrowding. This paper measures the association between LOS and factors that potentially contribute toLOS measured over consecutive shifts in the ED: shift 1 (7:
Niels K. Rathlev, MD, Dan Obendorfer, MBA, Laura F. White, PhD, Casey Rebholz, MPH, Brendan Magauran, MD, MBA, Willie Baker, MD, Andrew Ulrich, MD, Linda Fisher, RN, Jonathan Olshaker, MD   +8 more
doaj  

Length of postoperative stay prediction in elderly patients with hip fractures based on machine learning

Frontiers in Medicine
BackgroundLength of postoperative stay (LOPS) is an important indicator for resource allocation and clinical management in elderly patients with hip fractures.
Yanli Hu, Yanli Hu, Hong Qu, Feifan Wang, Fangfang Deng, Qun Luo, Tingting Gong   +6 more
doaj   +1 more source

Effect of Fresh Frozen Plasma Infusion on Hospital Length of Stay for Patients With Hereditary Angioedema [PDF]

# Background Patients with hereditary angioedema treated with fresh frozen plasma (FFP) infusion face complications and risk of side effects. # Objective To study the effect of FFP infusion on hospital length of stay for patients with hereditary ...
Alan T. Hitch, Subhan Khalid
core  

Reducing Length of Stay for Heart Failure Patients

, 2023
Using laminated cards on a cardiac intermediate floor has potential benefits such as improved intake and output documentation. This quality improvement study focused on patient-centered care and empowering the patients.
NC DOCKS at East Carolina University, Murphy, Jennifer   +1 more
core  

Length-of-stay in relation to number of mental comorbidities with outliers.

, 2023
μ: mean length-of-stay, plotted as diamonds; ci: 95% confidence interval, also shown by error bars; N: number of cases. The number of mental comorbidities on the x-axis is displayed up to 5, as the number of cases with 6 or 7 mental comorbidities is less
Christoph Nikendei (90906), Hans-Christoph Friederich (175289), Carsten Müller-Tidow (105305), Sophia Stahl-Toyota (16425836), Inga Unger (16425848), Norbert Frey (276344), Ede Nagy (16425839), Julia Szendrödi (16425851), Dirk Jäger (11106), Ivo Rollmann (16425845), Stefan Bönsel (16425842), Achim Hochlehnert (64812), Patrick Michl (832782)   +12 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Average Length of Stay in Hospitals

Journal of UOEH, 1984
The average length of stay is essentially an important and appropriate index for hospital bed administration. However, from the position that it is not necessarily an appropriate index in Japan, an analysis is made of the difference in the health care facility system between the United States and Japan.
openaire   +3 more sources