Results 21 to 30 of about 470,741 (269)

Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

open access: yesPharmaceutics, 2021
Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood–brain barrier (BBB), many CNS drugs treatments fail in clinical trials.
Elisa L. J. Moya   +7 more
doaj   +1 more source

Hydrophobic versus hydrophilic acrylic intraocular lens on posterior capsule opacification: a Meta-analysis [PDF]

open access: yesInternational Journal of Ophthalmology, 2022
AIM: To conduct a Meta-analysis pooling randomized controlled trials (RCTs) to compare hydrophobic with hydrophilic acrylic intraocular lenses in terms of posterior capsule opacification (PCO) development.
Qiong Wu, Yan Li, Lian Wu, Cong-Yi Wang
doaj   +1 more source

Colored visual stimuli evoke spectrally tuned neuronal responses across the central nervous system of zebrafish larvae

open access: yesBMC Biology, 2020
Background Visually guided behaviors such as optomotor and optokinetic responses, phototaxis, and prey capture are crucial for survival in zebrafish and become apparent after just a few days of development.
Chiara Fornetto   +3 more
doaj   +1 more source

Probing Globular Protein Self-Assembling Dynamics by Heterodyne Transient Grating Experiments

open access: yesApplied Sciences, 2019
In this work, we studied the propagation of ultrasonic waves of lysozyme solutions characterized by different degrees of aggregation and networking. The experimental investigation was performed by means of the transient grating (TG) spectroscopy as a ...
Sara Catalini   +4 more
doaj   +1 more source

The association between conjunctival and scleral thickness and ocular surface ultraviolet autofluorescence

open access: yesScientific Reports, 2023
Ultraviolet autofluorescence (UVAF) imaging is used to visualise ocular surface changes due to sunlight exposure and so is considered to be a biomarker for UV damage.
Pryntha Rajasingam   +5 more
doaj   +1 more source

SCHWARZ PROBLEM IN LENS AND HALF LENS

open access: yesEurasian Mathematical Journal, 2019
Summary: We consider the Schwarz boundary value problem (BVP) for the inhomogeneous Cauchy-Riemann equation in lenses and half lenses. By the technique of parqueting-reflection and the Cauchy-Pompeiu representation formula for lenses and half lenses, the Cauchy-Schwarz representation formula is obtained.
Joveini, Fatemeh, Akbari, Mozhgan
openaire   +2 more sources

Fiber-Based SERS-Fluidic Polymeric Platforms for Improved Optical Analysis of Liquids

open access: yesBioengineering, 2023
Downsizing surface-enhanced Raman spectroscopy (SERS) within microfluidic devices has opened interesting perspectives for the development of low-cost and portable (bio)sensors for the optical analysis of liquid samples. Despite the research efforts, SERS-
Caterina Credi   +6 more
doaj   +1 more source

Strong Noise Rejection in VLC Links under Realistic Conditions through a Real-Time SDR Front-End

open access: yesSensors, 2023
One of the main challenges in the deployment of visible light communication (VLC) in realistic application fields, such as intelligent transportation systems (ITSs), is represented by the presence of large background noise levels on top of the optical ...
Muhammad Ali Umair   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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