Results 21 to 30 of about 1,022,216 (261)

Miniaturization and Automation of a Human In Vitro Blood–Brain Barrier Model for the High-Throughput Screening of Compounds in the Early Stage of Drug Discovery

Pharmaceutics, 2021
Central nervous system (CNS) diseases are one of the top causes of death worldwide. As there is a difficulty of drug penetration into the brain due to the blood–brain barrier (BBB), many CNS drugs treatments fail in clinical trials.
Elisa L. J. Moya, Elodie Vandenhaute, Eleonora Rizzi, Marie-Christine Boucau, Johan Hachani, Nathalie Maubon, Fabien Gosselet, Marie-Pierre Dehouck   +7 more
doaj   +1 more source

Colored visual stimuli evoke spectrally tuned neuronal responses across the central nervous system of zebrafish larvae

BMC Biology, 2020
Background Visually guided behaviors such as optomotor and optokinetic responses, phototaxis, and prey capture are crucial for survival in zebrafish and become apparent after just a few days of development.
Chiara Fornetto, Natascia Tiso, Francesco Saverio Pavone, Francesco Vanzi   +3 more
doaj   +1 more source

Probing Globular Protein Self-Assembling Dynamics by Heterodyne Transient Grating Experiments

Applied Sciences, 2019
In this work, we studied the propagation of ultrasonic waves of lysozyme solutions characterized by different degrees of aggregation and networking. The experimental investigation was performed by means of the transient grating (TG) spectroscopy as a ...
Sara Catalini, Andrea Taschin, Paolo Bartolini, Paolo Foggi, Renato Torre   +4 more
doaj   +1 more source

The soft-focus lens and Anglo-American pictorialism [PDF]

, 2008
Electronic version excludes illustrations for which permission has not been granted by the rights holderThe history, practice and aesthetic of the soft focus lens in photography is elucidated and developed from its earliest statements of need to the ...
Young, William Russell
core   +2 more sources

The association between conjunctival and scleral thickness and ocular surface ultraviolet autofluorescence

Scientific Reports, 2023
Ultraviolet autofluorescence (UVAF) imaging is used to visualise ocular surface changes due to sunlight exposure and so is considered to be a biomarker for UV damage.
Pryntha Rajasingam, Alyra Shaw, Brett Davis, David Alonso-Caneiro, Jared Hamwood, Michael Collins   +5 more
doaj   +1 more source

Hydrophobic versus hydrophilic acrylic intraocular lens on posterior capsule opacification: a Meta-analysis [PDF]

International Journal of Ophthalmology, 2022
AIM: To conduct a Meta-analysis pooling randomized controlled trials (RCTs) to compare hydrophobic with hydrophilic acrylic intraocular lenses in terms of posterior capsule opacification (PCO) development.
Qiong Wu, Yan Li, Lian Wu, Cong-Yi Wang
doaj   +1 more source

BCLA CLEAR - Contact lens complications [PDF]

, 2021
Contact lens-related complications are common, affecting around one third of wearers, although most are mild and easily managed. Contact lenses have well-defined anatomical and physiological effects on the ocular surface and can result in other ...
Ajay Kumar Vijay, Carnt, Nicole, Wolffsohn, James S., Bakkar, May, Woods, Craig, Marasini, Sanjay, Tan, Jacqueline, Craig Woods, Heidi Wagner, May Bakkar, Stapleton, Fiona, Fiona Stapleton, Chalmers, Robin, James S. Wolffsohn, Sanjay Marasini, Jacqueline Tan, Ng, Alison, Nicole Carnt, Robin Chalmers, Wolffsohn, James S, Alison Ng, Wagner, Heidi, Vijay, Ajay Kumar   +22 more
core   +1 more source

Fiber-Based SERS-Fluidic Polymeric Platforms for Improved Optical Analysis of Liquids

Bioengineering, 2023
Downsizing surface-enhanced Raman spectroscopy (SERS) within microfluidic devices has opened interesting perspectives for the development of low-cost and portable (bio)sensors for the optical analysis of liquid samples. Despite the research efforts, SERS-
Caterina Credi, Caterina Dallari, Sara Nocentini, Gabriele Gatta, Elena Bianchi, Diederik S. Wiersma, Francesco S. Pavone   +6 more
doaj   +1 more source

Determinants of the frequency of contact lens wear

, 2013
Objectives\ud \ud To characterize and discover the determinants of the frequency of wear (FOW) of contact lenses.\ud \ud Methods \ud \ud Survey forms were sent to contact lens fitters in up to 40 countries between January and March every year for 5 ...
Morgan, Philip B., Efron, Nathan, Woods, Craig A., The International Contact Lens Prescribing Survey Consortium,   +3 more
core   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source