Results 41 to 50 of about 586,851 (132)

From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome

open access: yesJournal of Ophthalmology, 2018
Dysfunctional lens syndrome (DLS) is a term coined to describe the natural aging changes in the crystalline lens. Different alterations in the refractive properties and transparency of the lens are produced during the development of presbyopia and ...
Joaquín Fernández   +4 more
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Preclinical cataract masquerading as post-LASIK regression

open access: yesOman Journal of Ophthalmology, 2016
The purpose of this case report is to bring forth a rare clinical scenario where preclinical cataract mimics post-LASIK regression and to describe the role of aberrometry in detecting higher order aberrations (HOAs) and early lens changes.
Rohit Shetty   +3 more
doaj   +1 more source

Galactokinase 1 Positively Regulates Mitochondrial Respiration by Phosphorylating TIMM13 as a Protein Kinase

open access: yesAdvanced Science, EarlyView.
GALK1 acts as a protein kinase beyond the phosphorylation of galactose. GALK1 phosphorylates TIMM13 at Y73 in the cytoplasm. This phosphorylation prevents premature oxidative folding of TIMM13 and ensures its entrance into the intermembrane space of mitochondrion, positively regulating mitochondrial respiration.
Chang Woo Ko   +5 more
wiley   +1 more source

Corneal densitometry and biomechanical properties in patients with primary congenital glaucoma [PDF]

open access: yes, 2021
Objective: To describe corneal densitometry, topographic measurements, and biomechanical properties in patients with primary congenital glaucoma (PCG) and healthy patients. To examine correlations between variables and determine their glaucoma diagnostic
Morales Fernández, Laura   +19 more
core   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

open access: yesCytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith   +9 more
wiley   +1 more source

Influence of intraocular lens subsurface nanoglistenings on functional visual acuity. [PDF]

open access: yesPLoS ONE, 2017
To investigate the influence of intraocular lens subsurface nanoglistenings (SSNGs) on functional visual acuity (FVA), thirty-nine eyes of 29 patients were examined in this study.
Takahiro Hiraoka   +6 more
doaj   +1 more source

Adeno‐associated virus‐mediated restoration of NaV1.1 in targeted brain regions ameliorates epilepsy in symptomatic Dravet syndrome mice

open access: yesEpilepsia, EarlyView.
Abstract Objective Dravet syndrome (DS) is a developmental and epileptic encephalopathy primarily caused by haploinsufficiency of the SCN1A gene, which encodes the alpha subunit of NaV1.1 voltage‐gated sodium channel. The disease manifests with febrile and spontaneous seizures, developmental delay, cognitive impairment, and increased risk of sudden ...
Martina Mainardi   +4 more
wiley   +1 more source

Corneal and lens densitometry after corneal collagen cross-linking for keratoconus

open access: yesJournal of the Egyptian Ophthalmological Society, 2014
Purpose The study aimed at investigating retrospectively the values of corneal and lens densitometry using the Pentacam Scheimpflug system after corneal cross-linking (CXL). Materials and methods This study included 50 eyes of 50 patients who had undergone CXL for keratoconus.
HanyA Helaly, IhabM Osman
openaire   +1 more source

Evaluation of corneal and lens density changes after cross-linking in keratoconus

open access: yesDelta Journal of Ophthalmology, 2019
Background Corneal cross-linking (CXL) is an important modality for keratoconus therapy. Lens and corneal density are reported to change in keratoconus and with CXL. However, these changes are not well studied.
Lamyaa S Soliman   +3 more
doaj   +1 more source

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