Results 51 to 60 of about 586,851 (132)

Comparison of corneal and lens density measurements obtained by Pentacam and CASIA2 in myopes

open access: yesBMC Ophthalmology, 2023
Purpose To investigate the agreement between Pentacam and CASIA2 in the evaluation of corneal densities (CDs) and lens densities (LDs) in myopes. Methods Fifty-three patients (106 eyes) underwent comprehensive ophthalmologic examinations.
Yijia Xu   +5 more
doaj   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati   +6 more
wiley   +1 more source

Dealings between Cataract and Retinal Reattachment Surgery in PVR

open access: yesJournal of Ophthalmology, 2016
Introduction. To evaluate the impact of the eye lens status and oil side effects on the outcome of vitreoretinal surgery in retinal detachment with proliferative vitreoretinopathy (PVR) and a temporary silicone oil tamponade (SOT). Methods. 101 eyes were
Svenja Deuchler   +7 more
doaj   +1 more source

Repeatability of interpolated corneal tomography maps in healthy and keratoconus corneas before and after crosslinking

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate the repeatability of interpolated Pentacam HR elevation, densitometry and anterior chamber depth (ACD) map data before and after customized corneal crosslinking (CXL) in keratoconus (KC) and healthy eyes with low‐grade myopia (MY), including effects of KC severity.
Anneli Fredriksson   +2 more
wiley   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

open access: yesThe FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal   +18 more
wiley   +1 more source

Site‐specific O‐glycans influence lacritin structure and multimerization in tears

open access: yesProtein Science, Volume 35, Issue 11, November 2026.
Abstract Lacritin is an abundantly expressed glycoprotein in tear fluid and plays key roles in immune response, tear secretion, and bacterial killing. These biological functions are tightly regulated through several biochemical mechanisms including multimerization, proteolysis, and alternative splicing, especially within its C‐terminal domain.
Vincent Chang   +7 more
wiley   +1 more source

Monochromatic higher order aberrations in highly myopic eyes with Staphyloma

open access: yesBMC Ophthalmology, 2021
Background Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical counselling, specially when ...
Santiago Delgado-Tirado   +7 more
doaj   +1 more source

Arcuate kisspeptin neurons display two types of calcium events: Regulation by sex, gonads, and senktide

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 11, November 2026.
Abstract The pattern of gonadotropin‐releasing hormone (GnRH) release controls reproduction in vertebrates and is regulated by feedback from the gonads. Evidence is accumulating that steroid‐sensitive hypothalamic arcuate kisspeptin–neurokinin B–dynorphin (KNDy) neurons drive GnRH pulses.
R. Anthony DeFazio   +4 more
wiley   +1 more source

c‐Jun N‐Terminal Kinase‐2 Mediates Alcohol and Corticosterone‐Induced Tissue Injury at the Gut‐Liver Axis

open access: yesThe FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Alcohol activates JNK2, leading to epithelial TJ disruption. Corticosterone activates JNK2 and causes Paneth cell dysfunction. Depletion of α‐defensins due to Paneth cell dysfunction causes gut microbiota dysbiosis. Microbiota dysbiosis and TJ disruption lead to endotoxemia, systemic inflammation, and liver damage.
Lohitha Basa   +13 more
wiley   +1 more source

Thymic Stromal Lymphopoietin Promotes Proliferation and Contractility of Human Pulmonary Artery Smooth Muscle

open access: yesPulmonary Circulation, Volume 16, Issue 4, October 2026.
Thymic stromal lymphopoietin (TSLP) can be derived from pulmonary endothelial cells or smooth muscle, influencing TSLP‐R expressed by both cell types. Hypoxia enhances TSLP and TSLP‐R. TSLP enhances smooth muscle proliferation, fibrosis, and calcium/contractility responses to agonist. TSLP interacts with hypoxia by promoting HIF1‐α: effects relevant to
Michael Thompson   +5 more
wiley   +1 more source

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