Results 71 to 80 of about 586,851 (132)
mGluR5 in ECCCK to BLA Circuit Modulates Depressive‐Like Phenotypes through CCK Signaling
Advanced Science, Volume 13, Issue 43, 3 August 2026.Dysregulation of mGluR5 and CCK signaling contributes to major depressive disorder, yet circuit‐level mechanisms remain unclear. Here, the ECCCK→BLA pathway is identified as a critical regulator of affective behavior. mGluR5 modulates synaptic function and CCK signaling within this circuit, controlling stress susceptibility and depressive‐like states ...
Muhammad Asim +4 more
wiley +1 more source
Does HIV accelerate the aging process? An assessment of clinical, ophthalmic and serum parameters in HIV-infected individuals in South Africa [PDF]
HIV-infected individuals are at increased risk of age-related non-AIDS morbidity and mortality compared with HIV-uninfected persons. It is speculated that HIV-infected individuals may not only be aging chronologically, but also undergoing accelerated ...
Pathai, S
core +1 more source
The influence of center of gravity and lens mass on rigid lens dynamics [PDF]
, 1996 PURPOSE: Center of gravity and lens mass have both been shown to influence rigid lens centration and stability. The purpose of this study was to investigate the relative contributions of these two factors to rigid lens dynamics.
Carney, Leo G. +4 more
core
Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.In this study, Streather et al. show that the Vesicle Nucleating Peptide (VNp) drives formation of recombinant extracellular vesicles in E. coli that are compositionally distinct from native outer membrane vesicles (OMVs). Whereas OMVs contain heterogeneous periplasmic components and low, variable levels of recombinant cargo, Using a range of ...
Bree R. Streather +9 more
wiley +1 more source
The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes
The FEBS Journal, Volume 293, Issue 15, Page 4489-4507, August 2026.Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova +12 more
wiley +1 more source
The Influence of extracellular matrix on lens epithelial cell viability [PDF]
, 2006 Posterior capsular opacification is the main complication of cataract surgery and results from the proliferation, migration and differentiation of lens epithelial cells remaining in the capsular bag. To better understand this pathological cell behaviour,
Frederique, M D Tholozan +1 more
core
The FEBS Journal, Volume 293, Issue 15, Page 4624-4644, August 2026.Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf +7 more
wiley +1 more source
Cataract surgery in patients with corneal opacities
BMC Ophthalmology, 2018 Background Investigating the efficacy and safety of phacoemulsification with intraocular lens (IOL) implantation in corneal opacities. Methods This retrospective study was conducted in a tertiary medical center.
Yi-Ju Ho, Chi-Chin Sun, Hung-Chi Chen
doaj +1 more source
, 2005 The International Society for Clinical Densitometry (ISCD) has published position statements on topics relating to the use and interpretation of measurements of bone mineral density (BMD). The most recent appeared in the Journal of Clinical Densitometry (
Rizzoli, R +10 more
core +1 more source