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Lipid metabolism dysregulation in solar lentigo: a multi-system-level analysis reveals membrane instability and energy homeostasis disruption [PDF]
Frontiers in Cell and Developmental BiologySolar lentigo is a common hyperpigmented skin condition caused by chronic ultraviolet exposure, primarily affecting photoaged skin. While previous investigations focused on inflammatory and melanogenic mechanisms, the comprehensive role of lipid ...
Sohyun Kim +12 more
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Topical Imiquimod for Lentigo Maligna in a Nonagenarian [PDF]
LifeBackground: Lentigo maligna (LM) represents melanoma in situ and predominantly affects elderly individuals, typically arising on chronically sun-exposed skin of the head and neck.
Sarah Hosseini +2 more
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Actas Dermo-Sifiliográficas, 2022 Topical imiquimod has been used off-label as monotherapy or adjuvant treatment for lentigo maligna. Our aim is to describe treatment modalities, clinical outcomes, and management of recurrence in patients receiving imiquimod for lentigo maligna.Patients ...
I. Poveda-Montoyo +4 more
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Actas Dermo-Sifiliográficas, 2022 Resumen: Imiquimod tópico ha sido utilizado como monoterapia o tratamiento adyuvante fuera de indicación para el lentigo maligno (LM). Nuestro objetivo es describir las modalidades de tratamiento, los resultados clínicos y el manejo de la recidiva en los
I. Poveda-Montoyo +4 more
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[Translated article] Update on Lentigo Maligna: Diagnostic Signs and Treatment
Actas Dermo-Sifiliográficas, 2023 Lentigo maligna is an in situ cutaneous melanoma that arises in sun-damaged skin. Its most common presentation is a progressive, slow-growing, irregularly pigmented spot on the face of older patients. Although the exact percentage of lentigo maligna that
C. Requena, E. Manrique, E. Nagore
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El lentigo maligno: actualización y claves en el diagnóstico y el tratamiento
Actas Dermo-Sifiliográficas, 2023 Resumen: El lentigo maligno es un melanoma cutáneo in situ que asienta en zonas con daño solar acumulado. Su presentación más habitual es como una mancha irregularmente pigmentada de crecimiento lento y progresivo localizada en la cara de un paciente ...
C. Requena, E. Manrique, E. Nagore
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Dermatology Practical & Conceptual, 2023 Introduction: Lentigo maligna is a subtype of melanoma in situ that typically affects the head and neck region with an increasing incidence. Margin-controlled techniques, such as spaghetti technique (ST), have gained popularity over wide local excision (
Manel Martinez-Molina +8 more
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Synchronous conjunctival melanoma and lentigo maligna melanoma [PDF]
Anais Brasileiros de Dermatologia, 2017 : Lentigo maligna has an extensive and neoplastic character. It typically progresses slowly and may eventually develop into an invasive melanoma, which is called lentigo maligna melanoma. Ocular melanoma is the second most common type of melanoma.
Beatrice Mussio Fornazier Volpini +4 more
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Dermatology Practical & Conceptual, 2021 Pagetoid spread of melanocytes in the epidermis is a common indicator of melanocytic atypia, both histopathologically and with reflectance confocal microscopy (RCM).
Nadiya Chuchvara +4 more
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Actas Dermo-Sifiliográficas, 2013 Lentigo maligna is a type of in situ melanoma. It develops mainly in middle-aged and elderly individuals on areas of the skin chronically exposed to sunlight. It progresses to its invasive form, lentigo maligna melanoma, in 5% to 50% of cases. Management of lentigo maligna is open to debate, with a notable lack of randomized trials and specific ...
E, Samaniego, P, Redondo
openaire +2 more sources