Results 31 to 40 of about 10,843 (238)
Challenge in diagnosis and management of lentigo maligna and lentigo maligna melanoma [PDF]
Lentigo maligna (LM) is a subtype of melanoma in situ, which can evolve into lentigo maligna melanoma (LMM) if treated inadequately. LM and LMM are usually found on chronically sun damaged skin such as the face (cheek and nose) of the elderly on seventh ...
Ika Anggraini +4 more
doaj +1 more source
The most commonly used techniques for the in vivo evaluation of the cellular immune response include intracutaneous testing with microbial recall antigens or sensitization with neoantigens.
Bogner, Johannes R. +4 more
core +1 more source
Kartika Ruchiatan, Noer Olivy Alifiar, Diah Puspitosari, Reti Hindritiani Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr.
Ruchiatan K +3 more
doaj
SOX10 commonly stains scar in Mohs sections [PDF]
Sox10 immunostaining is used for the diagnosis and margin evaluation of melanocytic lesions. Sox10 was initially thought not to stain fibrohistiocytic processes.
Donaldson, Matthew R, Weber, L Arthur
core
Contoured technique for lentigo maligna [PDF]
The surgical approach to lentigo maligna is a challenge to dermatologists, given the difficulty of clinical delimitation of borders.
Monica Jidid Mateus +5 more
doaj +1 more source
In vitro evidence for senescent multinucleated melanocytes as a source for tumor-initiating cells [PDF]
Oncogenic signaling in melanocytes results in oncogene-induced senescence (OIS), a stable cell-cycle arrest frequently characterized by a bi- or multinuclear phenotype that is considered as a barrier to cancer progression.
Bröcker, E.-B. +12 more
core +2 more sources
Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies
ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio +16 more
wiley +1 more source
Comparison of SOX-10, HMB-45, and Melan-A in Benign Melanocytic Lesions
Sabrina E Dass,1 Taryn Huizenga,2 Mehdi Farshchian,2 Darius R Mehregan2 1Wayne State University School of Medicine, Detroit, MI, USA; 2Department of Dermatology, Wayne State University, Detroit, MI, USACorrespondence: Mehdi FarshchianDepartment of ...
Dass SE +3 more
doaj
Aim: The evaluation of the trend in the occurrence of melanoma nodulare, melanoma superficiale, lentigo maligna and melanoma in situ in the period of 2002–2017 in East Bohemia region in the Czech Republic.
Jarmila Čelakovská +4 more
doaj +1 more source
The 9th International RASopathies Symposium
ABSTRACT The RASopathies are a group of congenital disorders with overlapping clinical manifestations that are caused by pathogenic germline or early somatic variants that result in the hyperactivation of the RAS/mitogen‐activated protein kinase (MAPK) signaling pathway.
Pau Castel +41 more
wiley +1 more source

