Results 61 to 70 of about 5,863 (212)
Training of neural networks for automated diagnosis of pigmented skin lesions is hampered by the small size and lack of diversity of available datasets of dermatoscopic images. We tackle this problem by releasing the HAM10000 ("Human Against Machine with
Kittler, Harald +2 more
core +1 more source
Microinvasive lentigo maligna melanoma
Ninety-one skin biopsy specimens previously identified as lentigo maligna were examined for the presence of microinvasion, using the demonstration of S100 protein within atypical cells as the means for locating these superficial foci. In 14 cases, atypical melanocytes were identified, most often in the papillary dermis.
openaire +2 more sources
Abstract The current melanoma staging system predicts 74% of the variance in survival, with prognostic biomarkers subject to high levels of inter‐observer variation. This work assesses whether a previously developed convolutional neural network (CNN) for invasive melanoma segmentation in whole slide images (WSIs) may reveal new insights into melanoma ...
Emily L Clarke +15 more
wiley +1 more source
Dermatoscopic features of cutaneous non-facial and non-acral lentiginous growth pattern melanomas
Background: The dermatoscopic features of facial lentigo maligna (LM), facial lentigo maligna melanoma (LMM) and acral lentiginous melanoma (ALM) have been well described. This is the first description of the dermatoscopic appearance of a clinical series
Jeff Keir
doaj +1 more source
In vivo multimodal optical imaging of dermoscopic equivocal melanocytic skin lesions
There is a wide range of equivocal melanocytic lesions that can be clinically and dermoscopically indistinguishable from early melanoma. In the present work, we assessed the possibilities of combined using of multiphoton microscopy (MPM) and optical ...
V. Elagin +9 more
doaj +1 more source
Hypothyroidism as Prognostic Factor in Cutaneous Melanoma: A 1553‐Patient Single‐Center Study
ABSTRACT Background Cutaneous melanoma is a rising global health concern and identifying modifiable or associated risk factors remains essential for improving prognostic stratification. Hypothyroidism, affecting approximately 5.1% of the general population in Germany, has been associated with various malignancies. This study investigates the prevalence
Julie Klose +8 more
wiley +1 more source
SOX10 commonly stains scar in Mohs sections [PDF]
Sox10 immunostaining is used for the diagnosis and margin evaluation of melanocytic lesions. Sox10 was initially thought not to stain fibrohistiocytic processes.
Donaldson, Matthew R, Weber, L Arthur
core
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller +2 more
wiley +1 more source
Diagnosis and management of lentigo maligna: a review
Lentigo maligna is a melanocytic neoplasm occurring on sun-exposed skin, usually on the head and neck, of middle-aged and elderly patients. It is thought to represent the in situ phase of lentigo maligna melanoma.
Julia M Kasprzak, Yaohul G Xu
doaj +1 more source
Scalp Melanoma in a Young Patient With Systemic Sarcoidosis: Multidisciplinary Approach
ABSTRACT Often discovered at late stages, scalp melanoma presents unique diagnostic difficulties. Timely detection via public awareness, education, and comprehensive clinical assessment is essential for survival rate improvement. This case report shows the significance of multidisciplinary care and targeted therapies which can achieve remission even in
Nicolò Mori +17 more
wiley +1 more source

