Results 51 to 60 of about 3,530 (206)

Effects of Lentinan on Proliferation, Migration and Chemotherapy Sensitivity of Pancreatic Cancer Cells through the IL-6/STAT3/Notch Signaling Pathway

Shipin gongye ke-ji, 2023
Objective: Lentinan (LNT) had been shown to have direct cytotoxicity on cancer cells. However, the mechanism of this anti-tumor effect was still unclear.
Dong ZHANG, Tongxing DENG, Fenggang WANG, Xiaobo LIN, Jiexi CHENG, Yongchao MA   +5 more
doaj   +1 more source

Біологічна терапія, як допоміжне лікування раку шлунка (огляд літератури) [PDF]

, 2015
Представлений огляд робіт із використання препарату з гриба шиітаке лентинану для лікування раку шлунка. Препарат дозволений для використання в Японії. Розглянуті механізми дії препарату і поодинокі клінічні дослідження, що свідчать про доцільність його ...
Бодяка, Володимир Юрійович, Гушул, Іван Ярославович, Постевка, І.Д., Сенютович, Роман Васильович, Унгурян, Володимир Петрович, Чорний, Олег Васильович, Іващук, Олександр Іванович   +6 more
core  

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Lentinan-functionalized selenium nanoparticles induce apoptosis and cell cycle arrest in human colon carcinoma HCT-116 cells

Frontiers in Nutrition, 2022
Selenium nanoparticles (SeNPs) have gained extensive attention for their excellent biological activity and low toxicity. However, SeNPs are extremely liable to aggregate into non-bioactive or gray elemental selenium, which limits their application in the
Xiong Gao, Xiong Gao, Xiong Gao, Yanting Yao, Xujie Chen, Xiaorong Lin, Xiaobing Yang, Chi-Tang Ho, Bin Li, Bin Li, Zhongzheng Chen, Zhongzheng Chen   +11 more
doaj   +1 more source

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

Lentinan Inhibits AGE-Induced Inflammation and the Expression of Matrix-Degrading Enzymes in Human Chondrocytes

Drug Design, Development and Therapy, 2020
Zhaozhen Zhang, Zhuqing Zha, Zhiwei Zhao, Wenjing Liu, Wuyin Li Department of Bone Surgery, Luoyang Orthopedic Hospital of Henan Province (Henan Provincial Orthopedic Hospital), Zhengzhou City, Henan Province 450000, People’s Republic of ...
Zhang Z, Zha Z, Zhao Z, Liu W, Li W
doaj  

Lentinan-Based Oral Nanoparticle Loaded Budesonide With Macrophage-Targeting Ability for Treatment of Ulcerative Colitis

Frontiers in Bioengineering and Biotechnology, 2021
Ulcerative colitis (UC) is a global, chronic, and refractory disease. Corticosteroids are first-line drugs for the treatment of UC but also cause adverse side effects. Budesonide (BUD), a corticosteroid with relatively low side effects, has been approved
Meisi Lin, Meisi Lin, Meisi Lin, Lingling Dong, Qiyan Chen, Haiting Xu, Xiaoqin Han, Ruifeng Luo, Xiulan Pu, Shanshan Qi, Wenbiao Nie, Meilin Ma, Yitao Wang, Yitao Wang, Fei Gao, Jinming Zhang   +15 more
doaj   +1 more source

Sustainable Vitamin D2 Biofortification of Shiitake Mushrooms by Solar Drying

Advances in Agriculture, Volume 2026, Issue 1, 2026.
Vitamin D deficiency affects over 1 billion people and is linked to skeletal conditions such as rickets and osteoporosis, as well as nonskeletal and mental health disorders, including cardiovascular disease, certain cancers, infections, and depression.
Barbora Motýlová, Jan Tauchen, Ellyas Alga Nainggolan, Jan Banout, Deepika Kohli   +4 more
wiley   +1 more source

Kajian pendahuluan uji toksisitas ekstrak air miselia dan tubuh buah jamur shitake (Lentinus edodes) dengan metode brine shrimp lethality test (BTS)

Journal of Biological Researches, 2012
Shiitake mushroom (Lentinus edodes) is one of the wood mushroom types that can be consumed as a food as well as for a medicalpurpose. Lentinan, a polysaccharide contained in shiitake, is well known for its use on cancer medication.
Noor Erma NS, Tri Sundari, Arie Ika Susanty, Dwi Riani Octavia Palupi, Isnaeni Isnaeni, Sukardiman Sukardiman   +5 more
doaj   +1 more source

Metabolism and Biodegradation of β-Glucan in vivo

Frontiers in Veterinary Science, 2022
The β-Glucans widely exist in plants and edible fungi, and their diverse bioactivities and good physicochemical properties have been widely reported. In addition, β-glucan intravenous injections (such as lentinan and schizophyllan) have been clinically ...
Ziming Zheng, Ziming Zheng, Wenqi Tang, Weipeng Lu, Xu Mu, Yuxuan Liu, Xianglin Pan, Xianglin Pan, Kaiping Wang, Yu Zhang, Yu Zhang   +10 more
doaj   +1 more source