Results 191 to 200 of about 122,780 (298)
PEGylation of a Vesicular Stomatitis Virus G Pseudotyped Lentivirus Vector Prevents Inactivation in Serum [PDF]
Maria A. Croyle+7 more
openalex +1 more source
This study uncovers STAT6‐driven pulmonary fibrosis (PF) via suppression of PRKN‐mediated airway epithelial mitophagy, triggering mitochondrial dysfunction and ferroptosis. Rifabutin is identified as a potent STAT6 inhibitor that effectively reverses fibrotic progression. These findings reveal the STAT6‐PRKN axis as a pathogenic regulator and provide a
Youjing Yang+7 more
wiley +1 more source
Erratum: Lentivirus-mediated shRNA Targeting CNN2 Inhibits Hepatocarcinoma <i>in Vitro</i> and <i>in Vivo</i>: Erratum. [PDF]
Kang X+8 more
europepmc +1 more source
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu+8 more
wiley +1 more source
Retraction Note: Overexpression of HMGA1 promotes anoikis resistance and constitutive Akt activation in pancreatic adenocarcinoma cells. [PDF]
Liau SS, Jazag A, Ito K, Whang EE.
europepmc +1 more source
Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Xikai Liu+17 more
wiley +1 more source
Protocol for Generation of Single-Gene Knockout in Hard-to-Transfect THP1 Cell Lines Using CRISPR/Cas9. [PDF]
Srivastava K, Pandit B.
europepmc +1 more source