Results 231 to 240 of about 172,662 (343)

Bovine Lentivirus Group [PDF]

, 2020
openaire   +1 more source

Targeting G3BP1 Condensate Topology Promotes Stress Granule Assembly via m6A‐IGF2BP1 for Ischemic Stroke Rescue

Advanced Science, EarlyView.
Our research reveals that small‐molecule icariin (ICA) directly binds Ras‐GTPase‐activating protein SH3 domain‐binding protein 1 (G3BP1), inducing conformational change and oligomerization. This interaction confers neuroprotection by recruiting insulin‐like growth factor 2 mRNA‐binding protein 1 (IGF2BP1) and modulating N6‐methyladenosine (m6A ...
Ling Li, Yong‐Dong Guo, Xiao‐Wen Zhang, Zhi‐Yong Du, Yu‐Qi Wang, Zhuo Yang, Qian‐Wei Luo, Fang‐Fang Zhuo, Tian‐Tian Wei, Zheng‐Ping Liu, Bo Han, Wei Yu, Pei‐Pei Zhang, Wei Zhou, Zhi‐Yuan Lu, Peng‐Fei Tu, Chun‐Hong Zheng, Ke‐Wu Zeng   +17 more
wiley   +1 more source

Talin1 modulates the Piezo1-YAP axis to regulate endothelial cell inflammation and atherosclerosis. [PDF]

Cell Mol Life Sci
Wang Y, Huang H, Liu Z, Gao Z, Liao B, Long Y, Yu F, Nie Y.   +7 more
europepmc   +1 more source

754. Repeat Administration of Sendai Virus-F/HN Pseudotyped Lentivirus Vector to the Respiratory Epithelium Is Feasible

, 2008

openalex   +1 more source

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Engineered macrophages accumulate in solid tumors and locally deliver immune-activating proteins to inhibit tumor progression. [PDF]

Transl Cancer Res
Xu Y, Zhou Y, Wang J.
europepmc   +1 more source

In vivo gene delivery of urokinase‐type plasminogen activator with regulatable lentivirus induces behavioural changes in chronic cocaine administration [PDF]

, 2004
Amine Bahí, Frédéric Boyer, Christèle Gumy, Tal Kafri, Jean‐Luc Dreyer   +4 more
openalex   +1 more source

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

Inhibition of ICAM1 diminishes stemness and enhances antitumor immunity in glioblastoma via β-catenin/PD-L1 signaling. [PDF]

Nat Commun
Guo M, Yuan Z, Jin X, Li X, Deng Y, Zhou S, Niu R, Bae J, Park JB, Shi B, Yin J.   +10 more
europepmc   +1 more source

Co-delivery of Cas9/sgRNA RNPs and Vpx protein in lentivirus-derived nanoparticles for improved gene editing in THP-1 monocytic cells

David dos Santos Afonso
openalex   +1 more source