Results 261 to 270 of about 201,604 (308)

MMP14-Dependent Activation of TGF-β Signaling Enhances Malignancies via Promoting Necroptosis in Glioblastoma. [PDF]

FASEB J
Zhou H, Wu W, Cao Y, Zhang B, Zhou M, Wang Y, Wang M, Wang J.   +7 more
europepmc   +1 more source

LPAR1 Promotes Activation of Pathways Alveolar Hypercoagulation and Fibrinolytic Inhibition in ARDS via NF-κB Signaling Pathway. [PDF]

FASEB Bioadv
Liu Y, Chen X, Liu M, Yuan J, Li Q, Li L, Dong Q, Tao J, Shen F, Xiao C.   +9 more
europepmc   +1 more source

Amplicon sequencing with Oxford nanopore technologies as a diagnostic alternative for small ruminant lentiviruses in sheep. [PDF]

Sci Rep
Serrano M, González C, Roy R, Fernández A, Arranz JJ, Calvo JH, Jiménez MÁ, Puente-Sánchez F.   +7 more
europepmc   +1 more source

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Pathogenesis of lentivirus infections

Nature, 1986
Following infection of animals or humans, lentiviruses play a prolonged game of hide and seek with the host's immune system which results in a slowly developing multi-system disease. Emerging knowledge of the disease processes is of some relevance to acquired immune deficiency syndrome (AIDS), which is caused by a virus possessing many of the ...
Ashley T Haase
exaly   +3 more sources

Lentivirus Transgenesis

2010
Lentiviral transgenesis is a promising alternative to direct microinjection of DNA into pronuclei, which is by and large restricted to certain mouse strains. Lentiviruses are complex retroviruses that integrate their genome into the host chromosome.
Alexander, Pfeifer, Tiongti, Lim, Katrin, Zimmermann   +2 more
openaire   +2 more sources

Titration of Lentivirus Vectors

Cold Spring Harbor Protocols, 2018
The titer of a lentivirus vector is often expressed in transducing units per milliliter. This is a functional titer that reflects the lentivirus’ ability to transduce a particular cell line under specific conditions. Transduction of other cell lines is likely to be different and will require optimization.
Miguel, Sena-Esteves, Guangping, Gao
openaire   +2 more sources

Lentivirus-Mediated Gene Expression

2007
Lentiviruses have the capacity to enter and integrate their genetic material into cells that are not dividing. This property is retained in vectors based on these agents. They can thus effect gene delivery to cells that are difficult to transduce such as cardiac myocytes in vitro and in vivo.
Jing, Zhao, Andrew M L, Lever
openaire   +2 more sources

Lentivirus-Mediated Antagomir Expression

2010
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation via hybridisation to mRNAs. miRNA function can be inhibited by the so-called "antagomirs" - anti-sense RNA oligonucleotides complementary to individual miRNAs.
Ewa, Surdziel, Matthias, Eder, Michaela, Scherr   +2 more
openaire   +2 more sources

Lentivirus Replication and Regulation

Annual Review of Genetics, 1999
▪ Abstract  Lentiviruses are associated with chronic diseases of the hematological and neurological systems in animals and man. In particular, human immunodeficiency virus type 1 (HIV-1) is the etiological agent of the global AIDS epidemic. The genomes of lentiviruses are complex, encoding a number of regulatory and accessory proteins not found in ...
H, Tang, K L, Kuhen, F, Wong-Staal
openaire   +2 more sources