Results 301 to 310 of about 199,900 (336)

KBTBD11 loss promotes AKT hyperactivation and therapeutic vulnerability in prostate cancer. [PDF]

Oncogene
Sheng H, Shi G, Lu Y, Zheng S, Gu W, Xia D, Huang H, Ye D.   +7 more
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

TIPE2 deficiency enhances macrophage phagocytosis of tumor cells. [PDF]

J Immunother Cancer
Ma Z, Wang Y, Dong Y, Yuan H, Yang R, Xiao Y, Guo C, Wang R, Wang J, Wang X, Zhu F, Zhang L, Fan Y, Shi Y.   +13 more
europepmc   +1 more source

DCST1-AS1 promotes renal cell carcinoma progression via regulating the miR-582-5p/HMGB2 axis. [PDF]

J Transl Med
Dai C, Hu J, Tian X, Zhou H, Yang Z, Jin S, Zheng J.   +6 more
europepmc   +1 more source

Helicobacter pylori VacA modulates TRAF1-mediated 4-1BB/NF-kappaB axis to induce host apoptosis and chronic inflammatory damage. [PDF]

Mol Med
Yuan L, Yao S, Qu N, Li X, Yang X, Deng A, Zhang M, Cai T, Liang L, Liu Z, Liu X, Wang F.   +11 more
europepmc   +1 more source

A Novel Diagnostic Tool for West Nile Virus Lineage 1a and 2 Using a CRISPR-Cas12a System. [PDF]

Biosensors (Basel)
Hwang SB, Song YJ, Park PG.
europepmc   +1 more source

HER3 promotes triple-negative breast cancer progression by upregulating PHF8 via miR-34b-5p-dependent mechanism. [PDF]

Cell Death Dis
Lyu H, Tan C, Wu Y, Larsen ME, Yu Q, Kang G, Wood C, Tang SC, Liu B.   +8 more
europepmc   +1 more source

WNT pathway inhibition sensitizes HAT1-high lung cancers to treatment with PD-1 inhibitors. [PDF]

Cancer Cell Int
Yang T, Xie Z, Huang J, Zheng J, Zeng G, Yin X, Wang P, Chen L.   +7 more
europepmc   +1 more source

General methods: lentivirus production.

BioTechniques, 2010
openaire   +2 more sources

Engineering baculo- and lentiviral vectors for enhanced and targeted gene delivery (Geeninsiirron tehostaminen ja kohdentaminen pintamuokatuilla bakulo- ja lentiviruksilla) [PDF]

Kaikkonen, Minna
core