Results 11 to 20 of about 89 (88)
Twelve‐Month Real‐World Outcomes of Faricimab for Treatment‐Naive Neovascular AMD in Australia
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background To provide insights into the effectiveness and safety of faricimab for treatment‐naïve eyes with neovascular age‐related macular degeneration (nAMD). Methods A retrospective cohort study using a prospectively‐designed registry. Treatment‐naïve eyes with nAMD in Australia starting treatment with faricimab between Jan 2023–Sep 2024 ...
Mark Gillies +8 more
wiley +1 more source
NMR in Biomedicine, Volume 39, Issue 3, March 2026.Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila +10 more
wiley +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Advanced Biology, Volume 10, Issue 2, February 2026.Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Nanobiotechnology‐Based Approaches for Uveal Melanoma Treatment
SmartMat, Volume 7, Issue 1, February 2026.Emerging platforms for uveal melanoma combine precision drug delivery, ROS‐amplifying modalities, and nucleic acid transport to overcome ocular barriers and immunosuppressive niches. Targeted nanoparticles, virus‐like constructs, and injectable depots enable localized activation, controlled release, and gene‐level reprogramming.
Nadezhda A. Pechnikova +8 more
wiley +1 more source
Cardiovascular response to altered gravity in healthy adults: Insight from graded tilt testing
Physiological Reports, Volume 14, Issue 4, February 2026.Abstract Microgravity exposure during spaceflight induces a thoracocephalic fluid shift that affects the cardiovascular system both during flight and after return to Earth. As the proportion of female astronauts increases, it is essential to understand how altered gravity impacts cardiovascular function across sexes.
Adrien Robin +2 more
wiley +1 more source
Integrative cardiovascular dose–response to graded lower‐body negative pressure
Experimental Physiology, Volume 110, Issue 12, Page 1852-1879, December 1, 2025.ABSTRACT Lower‐body negative pressure (LBNP) has been posited as a potential spaceflight countermeasure to counteract the physiological deconditioning related to fluid shifts in microgravity. However, open questions remain regarding the magnitude of LBNP that should be applied.
Richard S. Whittle +5 more
wiley +1 more source
Diplostomum‐Induced Sac Formation in Lenses of Ameiurus Bullheads: A Host Defence Response?
Journal of Fish Diseases, Volume 48, Issue 10, October 2025.ABSTRACT Trematodes of the genus Diplostomum (Diplostomidae) are widely distributed and significant fish pathogens known for causing a range of negative effects. Any mechanism that protects the host from the parasite thus represents an evolutionary advantage.
Markéta Ondračková +6 more
wiley +1 more source
Corneal characteristics in children with Marfan syndrome with or without ectopia lentis
Pediatric Investigation, Volume 9, Issue 2, Page 160-166, June 2025.Children with Marfan Syndrome who have dislocation of the natural lens of the eye also have abnormalities of eye shape and size. These abnormalities are not apparent in Marfan's children who do not have lens dislocation, implying that the children with lens dislocation have a more severe genetic defect of fibrillin proteins.
Marisa O'Brien, Lawrence Tychsen
wiley +1 more source
Assessing UVA and Laser‐Induced Crosslinking via Brillouin Microscopy
Journal of Biophotonics, Volume 18, Issue 5, May 2025.UVA crosslinking is the primary treatment to combat keratoconus. Nevertheless, unwanted side effects and limitations due to nonselective irradiation lead to the investigation of alternative irradiation treatments. This study shows similar changes in the Brillouin frequency shift of corneas crosslinked with UVA irradiation and a NIR femtosecond laser ...
Christian A. Iriarte‐Valdez +8 more
wiley +1 more source
Acta Ophthalmologica, Volume 103, Issue 1, Page 43-49, February 2025.Abstract Purpose Treatment with glucocorticoids following paediatric cataract surgery is crucial to prevent inflammation, but may lead to secondary glaucoma, and hypothalamic–pituitary–adrenal axis suppression. We wish to compare glaucoma outcomes following high‐dose and low‐dose glucocorticoid treatment after paediatric cataract surgery.
Diana Chabané Schmidt +5 more
wiley +1 more source