Results 31 to 40 of about 388,084 (287)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
An accurate block error rate model for performance analysis of LEO NB-IoT communications systems
Discrete and Continuous Models and Applied Computational ScienceBackground: The extension of NB-IoT to LEO satellite systems enables mMTC in remote areas beyond terrestrial coverage. However, LEO NB-IoT faces significant physical layer challenges, including extreme path loss, rapid orbital dynamics, and blockage by ...
Danil V. Shilonosov +3 more
doaj +1 more source
Design and Manufacture of Thermal Model of AUTSAT Satellite and Its Thermal Balance Test [PDF]
فصلنامه علوم و فناوری فضایی, 2016 Base on space standards, the thermal design evaluations for satellites are performed using thermal balance tests. Regularly, the thermal model is used for the thermal balance test.
hamed Alisadesghi +2 more
doaj
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Correlation between Grades Earned and Time in Online Courses
Online Learning, 2017 Online education is rapidly becoming a significant method of course delivery in higher education. Consequently instructors are analyzing student performance in an attempt to better scaffold student learning.
Lin Carver, Keya Muhkerjee, Robert Lucio
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Sovremennye Issledovaniâ Socialʹnyh Problem, 2022 Purpose. The article is devoted to the study of methods used by teachers to enhance reading skills atforeign language lessonsusing mobile applications, which can be effectively used in the process of teaching/learning a foreign language, as well as the ...
Olga A. Kudinova +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
INTERVENTION PROGRAM FOR FL TEXT COMPREHENSION
Russian Journal of Education and Psychology, 2022 Purpose. The article is devoted to the study of an innovative method that can be used by teachers to develop reading skills in foreign language lessons, in particular, with the help of an intervention program for reading comprehension in English, which ...
Olga A. Kudinova, Valentina I. Kudinova
doaj +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source