Results 41 to 50 of about 988,991 (263)

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

Advanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo, Nuria Matesanz, Jorge‐Luis Torres, Alba C. Arcones, Juan Ignacio Jiménez‐Loygorri, Alfonso Mora, Leticia Herrera‐Melle, Luis Leiva‐Vega, Maria Elena Rodriguez, Lourdes Hernández‐Cosido, Marta Leon, Paula Yong González, Teresa Durán, Tamara Parracho, Francisca Mulero, Rubén Nogueiras, J. Simon C. Arthur, Angel R. Nebreda, Roger J. Davis, Miguel Marcos, Guadalupe Sabio   +20 more
wiley   +1 more source

A Robotic Testing Platform for Pipelined Discovery of Resilient Dielectric Elastomer Actuators

Advanced Science, EarlyView.
This work introduces a robotic testing platform enabling high‐throughput, multi‐parameter lifetime mapping of linear dielectric elastomer actuators (DEAs). By integrating programmable high‐voltage control and automated electromechanical measurements, the system identifies material and operating conditions that double actuator lifetime.
Ang (Leo) Li, Alexander Yin, Alexander White, Sahib Sandhu, Anatol Gogoj, Denise Maria de Andrade, Matthew Francoeur, Victor Jimenez‐Santiago, Van Remenar, Codrin Tugui, Mihai Duduta   +10 more
wiley   +1 more source

Mechanisms of Temperature‐Dependent Hysteresis in Freestanding BaTiO3/MoS2 Heterostructures

Advanced Science, EarlyView.
Freestanding ferroelectric BaTiO3 membranes are combined with monolayer MoS2 into 2D field‐effect transistors. At room temperature they provide ultrahigh‐κ gating with steep subthreshold swing and minimal hysteresis. Upon cooling, strong ferroelectric switching produces two stable memory states with long retention times.
Thomas Pucher, Federico Mompeán, Víctor Rouco, Carlos León, Jacobo Santamaría, Carmen Munuera, Mar García‐Hernández, Andres Castellanos‐Gomez   +7 more
wiley   +1 more source

Leonard pairs having LB–TD form

Linear Algebra and its Applications, 2014
Fix an algebraically closed field $\mathbb{F}$ and an integer $d \geq 3$. Let $\text{Mat}_{d+1}(\mathbb{F})$ denote the $\mathbb{F}$-algebra consisting of the $(d+1) \times (d+1)$ matrices that have all entries in $\mathbb{F}$. We consider a pair of diagonalizable matrices $A,A^*$ in $\text{Mat}_{d+1}(\mathbb{F})$, each acts in an irreducible ...
openaire   +3 more sources

Contact‐Free Human‐Machine Interfaces via Printed Thermopile Infrared Arrays

Advanced Science, EarlyView.
Can a printed sheet locate and sense a fingertip without being touched? Fully printed, flexible thermoelectric arrays convert the infrared from a hovering finger directly into voltage, with no external power. Aerosol‐jet‐printed silver mirrors partially shield each pixel, creating a local temperature gradient.
Zirui Wang, Nan Luo, Amrutha Bose, Muhammad Irfan Khan, Jiayi Liu, Leon Viktor Klinder, Leonard Franke, Mohamed Hussein, Uli Lemmer, Md Mofasser Mallick   +9 more
wiley   +1 more source

The Complete Inpatient Record Using Comprehensive Electronic Data (CIRCE) project: A team‐based approach to clinically validated, research‐ready electronic health record data

Learning Health Systems
Introduction The rapid adoption of electronic health record (EHR) systems has resulted in extensive archives of data relevant to clinical research, hospital operations, and the development of learning health systems.
Andrea L. C. Schneider, Jennifer C. Ginestra, Meeta Prasad Kerlin, Michael G. S. Shashaty, Todd A. Miano, Daniel S. Herman, Oscar J. L. Mitchell, Rachel Bennett, Alexander T. Moffett, John Chandler, Atul Kalanuria, Zahra Faraji, Nicholas S. Bishop, Benjamin Schmid, Angela T. Chen, Kathryn H. Bowles, Thomas Joseph, Rachel Kohn, Rachel R. Kelz, George L. Anesi, Monisha Kumar, Ari B. Friedman, Emily Vail, Nuala J. Meyer, Blanca E. Himes, Gary E. Weissman   +25 more
doaj   +1 more source

Normalized Leonard pairs and Askey–Wilson relations

Linear Algebra and its Applications, 2007
Let $V$ denote a vector space with finite positive dimension, and let $(A,B)$ denote a Leonard pair on $V$. As is known, the linear transformations $A,B$ satisfy the Askey-Wilson relations A^2B -bABA +BA^2 -g(AB+BA) -rB = hA^2 +wA +eI, B^2A -bBAB +AB^2 -h(AB+BA) -sA = gB^2 +wB +fI, for some scalars $b,g,h,r,s,w,e,f$.
openaire   +2 more sources

Integrating Automated Electrochemistry and High‐Throughput Characterization with Machine Learning to Explore Si─Ge─Sn Thin‐Film Lithium Battery Anodes

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
A closed‐loop, data‐driven approach facilitates the exploration of high‐performance Si─Ge─Sn alloys as promising fast‐charging battery anodes. Autonomous electrochemical experimentation using a scanning droplet cell is combined with real‐time optimization to efficiently navigate composition space.
Alexey Sanin, Jackson K. Flowers, Tobias H. Piotrowiak, Frederic Felsen, Leon Merker, Alfred Ludwig, Dominic Bresser, Helge Sören Stein   +7 more
wiley   +1 more source

Bond Energy Descriptors Enable Machine Learning With Limited Data: Design of Capping Agents for Thermoplastic Polyurethane Recycling

Advanced Intelligent Discovery, EarlyView.
Data scarcity is a critical bottleneck for machine learning in applied chemistry. We show that physics‐informed descriptors enable a simple linear model to predict the deblocking temperatures of capped diisocyanates to within 11 °C from just 19 measurements, demonstrating that embedding physical insight into descriptors, rather than relying on ...
Remsha Rafiq, Barbaro Zulueta, Hannah Zucco, Ramakrishna Suresh, Jason E. Shoemaker, Michael Call, Daylan Sheppard, Glenn Cormack, John A. Keith, Götz Veser   +9 more
wiley   +1 more source

Smart Bioinspired Material‐Based Actuators: Current Challenges and Prospects

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This work gathers, in a review style, an extensive and comprehensive literature overview on the development of autonomous actuators based on synthetic materials, bringing together valuable knowledge from several studies. Furthermore, the article identifies the fundamental principles of actuation mechanisms and defines key parameters to address the size
Alejandro Palacios, Léon Chiriatti, Simon Poppinga, Thomas Speck, Vincent Le Houérou   +4 more
wiley   +1 more source