"Reactions in Leprosy: Updated Insights Into Pathophysiology, Clinical Spectrum, and Therapeutic Approaches-A Narrative Review". [PDF]
ABSTRACT Background and Aims Reaction in leprosy is an immune‐mediated acute inflammatory episodes that occur in the natural course of Hansen's disease. Reaction can occur before, during, or after starting multidrug therapy and is a major cause of nerve damage, morbidity, and disability in affected individuals.
Gupta B +9 more
europepmc +2 more sources
Type 2 Lepra Reaction Following Antituberculosis Treatment Initiation in an Elderly Male With Coexisting Hansen's Disease: A Case Report. [PDF]
We report a case of a man developing erythema nodosum leprosum after initiating treatment for drug‐susceptible pulmonary tuberculosis. This highlights the importance of recognising concomitant leprosy in patients with tuberculosis since these mycobacterial infections require different long‐term multidrug regimens.
Villanueva CAG +3 more
europepmc +2 more sources
Coexistence of Scrofuloderma and Lepromatous Leprosy in Reaction: A Case Report. [PDF]
ABSTRACT Leprosy and tuberculosis (TB) are both chronic granulomatous infections caused by bacilli of the genus Mycobacterium. The simultaneous occurrence of cutaneous tuberculosis and leprosy is rare. We report a 56‐year‐old male presenting with painful erythematous nodules and plaques over the face and extremities for 1 week, along with asymptomatic ...
Khadka A +3 more
europepmc +2 more sources
Insights into global transcriptomic profile of biofilm producing Staphylococcus aureus clinical isolates from chronic foot ulcers [PDF]
Background and Objectives: Staphylococcus aureus (S. aureus) is one of the predominant biofilm producing pathogen in leprosy foot ulcer (LFU). The objective of this study was to identify the transcriptome profile through Next Generation Sequencing (NGS)
Kumar Ebineshan +2 more
doaj +2 more sources
Ein seltener Fall von lepromatöser Lepra in Deutschland [PDF]
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 11, Page 1454-1457, November 2025.
Saternus R +8 more
europepmc +2 more sources
Robust contact tracing and screening needed for leprosy control and protection of vulnerable children [PDF]
Leprosy in children is considered as an indicator of active disease transmission in the community. We report about a seven-year-old male from Telangana, India, with anesthetic skin lesions and familial leprosy history.
Khyathi Reddy Pilaka +3 more
doaj +2 more sources
Demyelinating Leprosy Neuropathy: An Unusual and Misleading Electrophysiological Pattern. [PDF]
ABSTRACT Introduction/Aims Peripheral neuropathy, especially mononeuropathy multiplex, is a frequent manifestation of leprosy. Electrodiagnostic studies (EDX) usually show predominant axonal involvement. In this study, we report patients with prominent demyelinating abnormalities consistent with the diagnosis of chronic inflammatory demyelinating ...
Foucard C +4 more
europepmc +2 more sources
Livedo reticularis in type 2 lepra reaction: A rare presentation
Type 2 lepra reaction or erythema nodosum leprosum (ENL) is an immune complex syndrome that occurs mostly in lepromatous leprosy and sometimes in borderline lepromatous leprosy patients.
Kikkeri Narayanasetty Naveen +3 more
doaj +3 more sources
Streptococcus dysgalactiae subsp.-equisimilis as an emerging secondary pathogen in leprosy foot ulcers [PDF]
Background and Objectives: Leprosy foot ulcers (LFU) tend to become chronic due to secondary bacterial infections, leading to subsequent disfigurement and disability.
Kumar Ebineshan +2 more
doaj +2 more sources
Lepra Bubalorum, a Potential Reservoir of Mycobacterium leprae [PDF]
In 1926, a mycobacterial skin disease was observed in water buffaloes by researchers in Indonesia. The disease was designated as skin tuberculosis, though it was hypothesized that it might be a form of leprosy or a leprosy-like disease. In a follow-up study (Ph.D.
William R. Faber +4 more
openaire +5 more sources

