Results 71 to 80 of about 18,492 (283)

The role of the A C395 IFNGR1 mutation in determining susceptibility to intracellular infection in Malta [PDF]

, 2012
Background: The first human mycobacterial susceptibility gene was identified amongst four children on the island of Malta in 1995. All affected children were homozygous for a nonsense mutation at position 395 of the interferon gamma receptor 1 (IFNGR1 ...
Anderson, Suzanne T., Attard Montalto, Simon, Felice, Alex, Hibberd, Martin, Levin, Mike, Mangion, Mariella, Newport, Melanie J.   +6 more
core  

Oro-facial aspects of leprosy : report of two cases with literature review [PDF]

, 2010
Leprosy is a chronic infectious disease affecting primarily the skin, peripheral nerves, respiratory system and the eyes. Leprosy induces various types of clinical presentation affecting the patient´s immune response.
Balachandran, Chandrasekharan, Gadda, Rohit Bhailal, Ghosh, Sujoy, Kudva, Ranjini, Pai, Keerthilatha M., Rao, Raghavendra, Vengal, Manoj   +6 more
core   +1 more source

Deep Vein Thrombosis in Lepromatous Leprosy: A Case Report of Secondary Pediatric Antiphospholipid Syndrome [PDF]

, 2022
Dyna Jones, Jayashankar CA, Amey Joshi, Shalini AS, Hemanth Kumar   +4 more
openalex   +1 more source

Serum Metabolomics Reveals Higher Levels of Polyunsaturated Fatty Acids in Lepromatous Leprosy: Potential Markers for Susceptibility and Pathogenesis

PLoS Neglected Tropical Diseases, 2011
Background Leprosy is a disease of the skin and peripheral nervous system caused by the obligate intracellular bacterium Mycobacterium leprae. The clinical presentations of leprosy are spectral, with the severity of disease determined by the balance ...
Reem Al-Mubarak, J. V. Vander Heiden, C. Broeckling, M. Balagon, P. Brennan, V. Vissa   +5 more
semanticscholar   +1 more source

Serological Evidence of Soil‐Transmitted Helminth Infections as a Potential Risk for Severity in Leprosy Patients

Tropical Medicine &International Health, Volume 30, Issue 10, Page 1115-1123, October 2025.
ABSTRACT Leprosy presents a broad clinical spectrum influenced by the host's immune response, and co‐infections may further modulate disease progression. This study evaluated clinically diagnosed leprosy patients (n = 251) from Sergipe and Minas Gerais, Brazil, along with healthy controls (n = 43), soil‐transmitted helminths‐positive controls (n = 15),
Ana Laura Grossi de Oliveira, Augusto César Parreiras de Jesus, Ramayana Morais de Medeiros Brito, Jordânia Costa‐Pinto, Tatyane Martins Cirilo, José Bryan Rihs, Marcelo Eduardo Cardozo, Lilian Lacerda Bueno, Luisa Mourão Dias Magalhães, Ricardo Toshio Fujiwara   +9 more
wiley   +1 more source

LEPROMATOUS LEPROSY [PDF]

The Lancet, 1968
N B, Rabhan, D S, Waldorf
  +8 more sources

Leprosy presenting with iridocyclitis: A diagnostic dilemma

Journal of Ophthalmic & Vision Research, 2017
Purpose: To report a case of lepromatous iridocyclitis that posed a diagnostic challenge. Case Report: A 50-yeasr-old male developed profound loss of vision in the right eye, while he was in the hospital with septicemia presenting with fever, dysuria ...
Jaya Kaushik, Vaibhav Kumar Jain, Jitendra Kumar Singh Parihar, Sanjay Dhar, Savita Agarwal   +4 more
doaj   +1 more source

Atypical Manifestations of Old World Cutaneous Leishmaniasis: A Systematic Review and Clinical Atlas of Unusual Clinical and Specific Anatomical Presentations

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Cutaneous leishmaniasis (CL) represents the most common form of leishmaniasis. It imposes a significant medical burden due to long‐lasting ulcers and disfiguring scars, underscoring the need for comprehensive CL control strategies, particularly in endemic regions.
Bahareh Abtahi‐Naeini, Seyed Naser Emadi, Zabihollah Shahmoradi, Mahsa Pourmahdi‐Boroujeni, Ali Saffaei, Fereshte Rastegarnasab   +5 more
wiley   +1 more source

Histoid leprosy: Role of fine needle aspiration cytology in the diagnosis

Journal of the Scientific Society, 2012
Histoid leprosy is a distinct variant of lepromatous leprosy. It presents clinically as well demarcated cutaneous and subcutaneous nodules similar to dermatofibroma.
Sunita Y Patil, Rajeev A Malipatil
doaj   +1 more source

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James, Madigan, Cressida A, Ramakrishnan, Lalita   +2 more
core   +2 more sources