Results 81 to 90 of about 9,518 (197)

Combined therapy in leprosy : background and findings [PDF]

open access: yes, 1978
This report is based on data obtained from 64 lepromatous cases. Despite many years of DDS monotherapy, the homogenates from biopsies of these patients revealed 104 or more bacteria.
Bonnici, Edgar   +4 more
core  

Localized borderline lepromatous leprosy

open access: yesLeprosy Review, 1991
A 48-year-old soldier presented with 3 small leprosy lesions localized over the flexor area of the forearm. There was no nerve thickening and clinically the lesions looked like borderline-tuberculoid leprosy. However, these lesions demonstrated a bacteriological index (BI) of 4+ while no acid-fast bacilli (AFB) could be demonstrated from any other site
P K, Jha   +3 more
openaire   +2 more sources

Polymorphisms in Toll-like receptor 4 ( TLR4 ) are associated with protection against leprosy [PDF]

open access: yes, 2018
Accumulating evidence suggests that polymorphisms in Toll-like receptors (TLRs) influence the pathogenesis of mycobacterial infections, including leprosy, a disease whose manifestations depend on host immune responses.
Abraham, I.   +10 more
core  

Safety and Availability of Clofazimine in the Treatment of Multidrug and Extensively Drug-Resistant Tuberculosis: Analysis of Published Guidance and Meta-Analysis of Cohort Studies [PDF]

open access: yes, 2013
Objectives: Given the spread of multidrug-resistant tuberculosis (MDR-TB), new therapies are urgently needed, including the repurposing of existing drugs. We aimed to assess key considerations for the clinical and programmatic use of clofazimine (Cfz), a
Dotsenko, Svetlana   +9 more
core   +1 more source

Lepromatous leprosy and human immunodeficiency virus co-infection associated with phenomenon of Lucio versus immune reconstitution inflammatory syndrome

open access: yesInfectio
: Diffuse lepromatous leprosy (DLL) is a severe clinical outcome of lepromatous leprosy (LL). The aetiologic cause is believed to be different from Mycobacterium leprae.
Héctor Alejandro Serrano-Coll   +3 more
doaj   +1 more source

Histoid leprosy in a 12-year-old child: A rare presentation

open access: yesIndian Journal of Paediatric Dermatology, 2016
Histoid leprosy is a clinical variant of nodular form of lepromatous leprosy. De novo histoid leprosy in children is a rare clinical presentation. We hereby report a case of a 12-year-old child presenting with lesions of histoid leprosy.
Sandeep Anilrao Kulkarni   +2 more
doaj   +1 more source

Hanseniase neural primaria: revisao sistematica [PDF]

open access: yes, 2013
The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels
Andrada, Nathalia Carvalho de   +13 more
core   +2 more sources

Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms

open access: yesJournal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed   +8 more
wiley   +1 more source

Arthritis in Leprosy Without Specific Skin Lesion [PDF]

open access: yes, 2010
Leprosy patients could display a great variability of signs and symptoms. An overabundance of rheumatic manifestations, occuring alone or in varying combinations, are associated with leprosy, particularly with lepra reactions A study involving seventy ...
Dewi, S. (Sumartini)   +1 more
core  

Immunohistochemical characterization of the M4 macrophage population in leprosy skin lesions

open access: yesBMC Infectious Diseases, 2018
Background Since macrophages are one of the major cell types involved in the Mycobacterium leprae immune response, roles of the M1 and M2 macrophage subpopulations have been well defined. However, the role of M4 macrophages in leprosy or other infectious
Jorge Rodrigues de Sousa   +3 more
doaj   +1 more source

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