Results 81 to 90 of about 9,180 (202)

Safety and Availability of Clofazimine in the Treatment of Multidrug and Extensively Drug-Resistant Tuberculosis: Analysis of Published Guidance and Meta-Analysis of Cohort Studies [PDF]

, 2013
Objectives: Given the spread of multidrug-resistant tuberculosis (MDR-TB), new therapies are urgently needed, including the repurposing of existing drugs. We aimed to assess key considerations for the clinical and programmatic use of clofazimine (Cfz), a
Dotsenko, Svetlana, Falzon, Dennis, Hwang, Thomas J, Jafarov, Azizkhon, Jaramillo, Ernesto, Keshavjee, Salmaan A., Lunte, Kaspars, Nunn, Paul, Wares, Douglas F., Weyer, Karin   +9 more
core   +1 more source

Beyond Elimination: Unveiling Leprosy Cases in Far West Nepal

Clinical Case Reports, Volume 13, Issue 6, June 2025.
ABSTRACT Leprosy, one of the Neglected Tropical Diseases (NTDs), can be diagnosed based on any of its three characteristics: a hypopigmented or reddish skin patch with sensory loss, thickened peripheral nerves with sensory impairment, and a positive skin smear for acid‐fast bacilli (AFB).
Smriti Lama Thing, Deepak Subedi, Anita Tamang Waiba, Neha Bista, Apsara Hamal, Monika Gurung   +5 more
wiley   +1 more source

Hanseniase neural primaria: revisao sistematica [PDF]

, 2013
The authors proposed a systematic review on the current concepts of primary neural leprosy by consulting the following online databases: MEDLINE, Lilacs/SciELO, and Embase. Selected studies were classified based on the degree of recommendation and levels
Andrada, Nathalia Carvalho de, Antunes, Sergio L., Barreira, Amilton Antunes, Barreto, Jaison Antonio, Carvalho, Noemia Barbosa, Floriano, Marcos César, Garbino, Jose Antonio, Heise, Carlos Otto, Marques Junior, Wilson, Nery, Jose Augusto, Rodrigues, Marcia Maria Jardim, Soares, Cleverson Teixeira, Trindade, Maria Angela Bianconcini, Virmond, Marcos da Cunha Lopes   +13 more
core   +2 more sources

Atypical presentation of disseminated mycobacteriosis due to Mycobacterium avium in an aged cat

Australian Veterinary Journal, Volume 103, Issue 3, Page 121-126, March 2025.
In cats, mycobacteriosis tends to present in a syndromic manner, with cases either being due to tuberculosis (TB) (in countries where TB is endemic), one of the “leprosy‐like” diseases affecting the skin and subcutis, panniculitis caused by infection of subcutaneous tissues generally with rapidly growing Mycobacteria spp.
A Teh, J Robertson, SL Donahoe, T Crighton, S Boyd, R Malik   +5 more
wiley   +1 more source

Histoid leprosy in a 12-year-old child: A rare presentation

Indian Journal of Paediatric Dermatology, 2016
Histoid leprosy is a clinical variant of nodular form of lepromatous leprosy. De novo histoid leprosy in children is a rare clinical presentation. We hereby report a case of a 12-year-old child presenting with lesions of histoid leprosy.
Sandeep Anilrao Kulkarni, Namrata Chhabra, Neel Prabha   +2 more
doaj   +1 more source

Leprosy-specific oral lesions : a report of three cases [PDF]

, 2008
Leprosy is a chronic infection caused by Mycobacterium leprae, a bacillus that presents a peculiar tropism for the skin and peripheral nerves. The clinical spectrum of leprosy ranges from the tuberculoid form (TT) to the disseminative and progressive ...
Arruda, Darlene, Foss, Norma Tiraboschi, Furini, Renata Bazan, Komesu, Marilena C., Motta, Ana C.F., Silva, Claudia Helena lovato, Simao, Joao Carlos Lopes, Zenha, Erika Muller Ramalho   +7 more
core  

Use of anti-PGL-1 antibodies to monitor therapy regimes in leprosy patients [PDF]

, 2009
The suitability of IgM antibodies to PGL-1 for monitoring the response to multidrug therapy (MDT) was sequentially tested by ELISA in 105 leprosy patients, and bacterial indexes (BI) were also determined.
FERREIRA, M.A.N., FOSS, N.T., ZENHA, E.M.R.   +2 more
core   +2 more sources

Bullous Type 2 Lepra Reaction: A Rare and Significant Case Report

Clinical Case Reports, Volume 13, Issue 1, January 2025.
ABSTRACT Bullous type 2 lepra reactions are a rare initial presentation in leprosy that can complicate the disease with vesiculo‐bullous lesions. Early recognition and differentiation from other bullous disorders are critical for timely corticosteroid and multidrug therapy initiation to improve patient outcomes.
Hrithik Dakssesh Putta Nagarajan, Balakrishnan Kamaraj, Keerthivasan Selvanathan, Pruthvi Raj Kukunoor, Katta Manichandana, Katta Manideep, Biki Kumar Sah   +6 more
wiley   +1 more source

Lepromatous leprosy and human immunodeficiency virus co-infection associated with phenomenon of Lucio versus immune reconstitution inflammatory syndrome

Infectio
: Diffuse lepromatous leprosy (DLL) is a severe clinical outcome of lepromatous leprosy (LL). The aetiologic cause is believed to be different from Mycobacterium leprae.
Héctor Alejandro Serrano-Coll, Juan Camilo Beltrán-Alzate, Sonia Milena Buitrago, Nora Cardona-Castro   +3 more
doaj   +1 more source

Immunohistochemical characterization of the M4 macrophage population in leprosy skin lesions

BMC Infectious Diseases, 2018
Background Since macrophages are one of the major cell types involved in the Mycobacterium leprae immune response, roles of the M1 and M2 macrophage subpopulations have been well defined. However, the role of M4 macrophages in leprosy or other infectious
Jorge Rodrigues de Sousa, Francisco Dias Lucena Neto, Mirian Nacagami Sotto, Juarez Antonio Simões Quaresma   +3 more
doaj   +1 more source