Results 31 to 40 of about 185,309 (316)

A Zebrafish Model of Mycobacterium leprae Granulomatous Infection. [PDF]

, 2017
Understanding the pathogenesis of leprosy granulomas has been hindered by a paucity of tractable experimental animal models. Mycobacterium leprae, which causes leprosy, grows optimally at approximately 30°C, so we sought to model granulomatous disease in
Cameron, James, Madigan, Cressida A, Ramakrishnan, Lalita   +2 more
core   +2 more sources

Stigma, participation restriction and mental distress in patients affected by leprosy, cutaneous leishmaniasis and Chagas disease: a pilot study in two co-endemic regions of eastern Colombia

Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020
Background Leprosy, cutaneous leishmaniasis (CL) and Chagas disease (CD) are neglected tropical diseases with a high psychosocial burden (PSB). These conditions are endemic in Norte de Santander and Arauca in Colombia, but data on the related PSB are ...
Libardo J Gómez, Robin van Wijk, Lena van Selm, A. Rivera, M. C. Barbosa, Sandra Parisi, W. V. van Brakel, Jofren Arevalo, William Quintero, M. Waltz, K. Puchner   +10 more
semanticscholar   +1 more source

Incidence of and Factors Associated With Leprosy Among Household Contacts of Patients With Leprosy in Brazil

JAMA dermatology, 2020
This cohort study evaluates the incidence of leprosy among household contacts of patients with leprosy in Brazil and the factors associated with development of leprosy in these contacts.
Camila Silveira Silva Teixeira, J. Pescarini, Flávia Jôse Oliveira Alves, J. Nery, Mauro Niskier Sanchez, Carlos Teles, M. Y. Ichihara, A. Ramond, L. Smeeth, Maria Lúcia Fernandes Penna, L. Rodrigues, E. Brickley, G. Penna, Mauricio L. Barreto, Rita de Cássia Ribeiro Silva   +14 more
semanticscholar   +1 more source

Leprosy in elderly and children among new cases – A 3-year retrospective study

Indian Dermatology Online Journal, 2021
Background: Leprosy occurs in all age groups, with adults constituting the majority. However, leprosy in children always drew the attention of epidemiologists as a guide to transmission of leprosy.
Potharaju Arunraghav, Kallappa Herakal
doaj   +1 more source

Clustering of leprosy beyond the household level in a highly endemic setting on the Comoros, an observational study

BMC Infectious Diseases, 2019
Background The island of Anjouan (Comoros) is highly endemic for leprosy with an annual incidence of 5–10/10,000. In May/June, 2015 single-dose Rifampicin post-exposure prophylaxis (SDR-PEP) was administered to 269 close contacts of 70 leprosy-patients ...
Nimer Ortuno-Gutierrez, Abdallah Baco, Sofie Braet, Assoumani Younoussa, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Bouke C. de Jong, Jan Hendrik Richardus, Epco Hasker   +10 more
doaj   +1 more source

Illness perceptions of leprosy-cured individuals in Surinam with residual disfigurements – “I am cured, but still I am ill” [PDF]

, 2016
Objective Leprosy has rarely been the subject of health psychology research despite its substantial impact. Our aim was to explore illness perceptions in patients and their health care providers in Surinam.
Kaptein, Ad A., Lawrence, Maggie, Menke, Jack, Reyme, Melinda, van Haaren, Mark A.C.   +4 more
core   +1 more source

The Impact of Leprosy on Marital Relationships and Sexual Health among Married Women in Eastern Nepal

Journal of Tropical Medicine, 2016
Background. Leprosy is one of the most stigmatized diseases known today. The stigma surrounding leprosy can be a major burden and affects many dimensions of a person’s life, including intimate relationships.
Anna T. van ’t Noordende, Wim H. van Brakel, Nandlal Banstola, Krishna P. Dhakal   +3 more
doaj   +1 more source

Cytosolic proteome profiling of aminoglycosides resistant Mycobacterium tuberculosis clinical isolates using MALDI-TOF/MS

Frontiers in Microbiology, 2016
Emergence of extremely drug resistant tuberculosis (XDR-TB) is the consequence of the failure of second line TB treatment. Aminoglycosides are the important second line anti-TB drugs used to treat the multi drug resistant tuberculosis (MDR-TB).
Divakar Sharma, Manju Lata, Rananjay Singh, Nirmala Deo, Krishnamurthy Venkatesan, Deepa Bisht   +5 more
doaj   +1 more source

Dermoscopy in Leprosy: A Clinical and Histopathological Correlation Study

Dermatology Practical & Conceptual, 2021
Background: Leprosy, an insidious infectious granulomatous disease, is diagnosed traditionally through clinical examination coupled with skin smears and histopathology. It has myriad clinical presentations that pose diagnostic challenges.
Alpana Mohta, Suresh Kumar Jain, Aditi Agrawal, Ramesh Kumar Kushwaha, Pritee Sharma, Khusbhoo Sethia, Manish Jain   +6 more
doaj   +1 more source

Protocol, rationale and design of PEOPLE (Post ExpOsure Prophylaxis for LEprosy in the Comoros and Madagascar): a cluster randomized trial on effectiveness of different modalities of implementation of post-exposure prophylaxis of leprosy contacts

BMC Infectious Diseases, 2019
Background Leprosy is an ancient infectious disease with a global annual incidence that has plateaued above 200,000 new cases since over a decade. New strategies are required to overcome this stalemate.
Nimer Ortuno-Gutierrez, Assoumani Younoussa, Andriamira Randrianantoandro, Sofie Braet, Bertrand Cauchoix, Stéphanie Ramboarina, Abdallah Baco, Aboubacar Mzembaba, Zahara Salim, Mohamed Amidy, Saverio Grillone, Jan Hendrik Richardus, Bouke C. de Jong, Epco Hasker   +13 more
doaj   +1 more source